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News tagged with estrogen

Estrogen levels tied to risk for sudden cardiac death in study

(HealthDay)—Higher levels of the hormone estrogen are associated with an increased risk of sudden cardiac death in men and women, a new study suggests.

Cardiology created May 11, 2013 | popularity 4.5 / 5 (2) | comments 0

Brain anatomy of dyslexia is not the same in men and women, boys and girls

Using MRI, neuroscientists at Georgetown University Medical Center found significant differences in brain anatomy when comparing men and women with dyslexia to their non-dyslexic control groups, suggesting that the disorder ...

Neuroscience created May 08, 2013 | popularity 2 / 5 (1) | comments 0

Exercise-related changes in estrogen metabolism may lower breast cancer risk

Changes in estrogen breakdown, or metabolism, may be one of the mechanisms by which aerobic exercise lowers a woman's breast cancer risk, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a jour ...

Cancer created May 07, 2013 | popularity 5 / 5 (1) | comments 0

Low-dose 'pill' linked to pain during orgasm, study finds

(HealthDay)—Women taking birth control pills with lower amounts of estrogen—a commonly prescribed contraceptive—may be at higher risk for chronic pelvic pain and pain during orgasm, according to new ...

Medications created May 03, 2013 | popularity not rated yet | comments 0 | with audio podcast

Estrogen fuels autoimmune liver damage

A life-threatening condition that often requires transplantation and accounts for half of all acute liver failures, autoimmune hepatitis is often precipitated by certain anesthetics and antibiotics. Researchers say these ...

Medical research created Apr 30, 2013 | popularity 5 / 5 (2) | comments 0

Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary ...

Cancer created Apr 23, 2013 | popularity 5 / 5 (1) | comments 0

Cold winters freezing out breast cancer treatment

For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer. Currently, tamoxifen ...

Cancer created Apr 18, 2013 | popularity not rated yet | comments 0

Spread of breast cancer linked to kisspeptins which normally inhibit metastasis

KISS 1 is a metastasis-suppressor gene which helps to prevent the spread of cancers, including melanoma, pancreatic and ovarian cancers to name a few. But new research from Western University's Schulich School of Medicine ...

Cancer created Apr 16, 2013 | popularity not rated yet | comments 0

Polymorphism in estrogen receptor alpha linked to back pain

(HealthDay)—For women with degenerative spondylolisthesis (DS), polymorphisms in the estrogen receptor α (ERα) are associated with back pain intensity, according to a study published in the April issue ...

Diseases, Conditions, Syndromes created Apr 11, 2013 | popularity not rated yet | comments 1

Pfizer breast cancer drug gets breakthrough label

Pfizer Inc. says its experimental pill for advanced, often deadly breast cancer has been designated as a breakthrough therapy by the Food and Drug Administration.

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

New approach evaluates effect of physical activity on estrogen metabolism in postmenopausal women

Researchers have generated new insights into the ways in which physical activity affects how much estrogen is broken down and secreted in the urine of postmenopausal women. These findings enhance understanding of the potential ...

Cancer created Apr 10, 2013 | popularity not rated yet | comments 0

Studies show increasing evidence that androgen drives breast cancer

Estrogen and progesterone receptors, and the gene HER2 – these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Paragazole excels in preclinical models of triple-negative breast cancer

Breast cancers that lack estrogen receptors are more difficult to treat than ER+ cancers. Research presented at the AACR Annual Meeting 2013 demonstrates an investigational drug, Paragazole, that makes triple-negative ...

Cancer created Apr 08, 2013 | popularity 5 / 5 (2) | comments 0

Estrogen plus progestin use linked with increased breast cancer incidence and mortality

Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be ...

Cancer created Mar 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Combinations of estrogen-mimicking chemicals found to strongly distort hormone action

For years, scientists have been concerned about chemicals in the environment that mimic the estrogens found in the body. In study after study, researchers have found links between these "xenoestrogens" and such problems as ...

Health created Mar 28, 2013 | popularity 3.7 / 5 (3) | comments 0

Estrogen

Estrogens (U.S., otherwise oestrogens or œstrogens) are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone, their name comes from estrus (period of fertility for female mammals) + gen = to generate.

Estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for postmenopausal women, and in hormone replacement therapy for transwomen.

Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen receptors which in turn up-regulate the expression of many genes. Additionally, estrogens have been shown to activate a G protein-coupled receptor, GPR30.

For more information about Estrogen, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.