For reasons unknown, many patients with breast cancer treated with the estrogen receptor-blocking drug tamoxifen eventually become resistant to the treatment despite the fact that their cancer cells still have the estrogen ...
Birth control pills cause a small but significant increase in the risk of the most common type of stroke, according to a comprehensive report in the journal MedLink Neurology.
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Estrogens (U.S., otherwise oestrogens or œstrogens) are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone, their name comes from estrus (period of fertility for female mammals) + gen = to generate.
Estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for postmenopausal women, and in hormone replacement therapy for transwomen.
Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen receptors which in turn up-regulate the expression of many genes. Additionally, estrogens have been shown to activate a G protein-coupled receptor, GPR30.
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