Oncology & Cancer

Exploring tumor evolution

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer ...

Genetics

Evolving genes lead to evolving genes

Researchers have designed a method that can universally test for evolutionary adaption, or positive (Darwinian) selection, in any chosen set of genes, using re-sequencing data such as that generated by the 1000 Genomes Project. ...

Medical research

Using human brain cells to make mice smarter

Glial cells – a family of cells found in the human central nervous system and, until recently, considered mere "housekeepers" – now appear to be essential to the unique complexity of the human brain. Scientists reached ...

Genetics

Following the footprints of positive selection

For decades, the human genome could only tell us what we already suspected about the evolution of certain traits. Researchers were able to trace the genetic origin stories of lactose tolerance (as opposed to lactose intolerance), ...

Genetics

Evolution's gift may also be at the root of a form of autism

A recently evolved pattern of gene activity in the language and decision-making centers of the human brain is missing in a disorder associated with autism and learning disabilities, a new study by Yale University researchers ...

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