Mice with 'humanized' livers improve early drug testing
Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.
Medical research
Oct 31, 2012 |
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Mouse model exposes a new type of T cell to target melanoma
Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow ...
Cancer
Oct 24, 2012 |
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Researchers' discovery revives hope in promising lymphoma treatment
(Medical Xpress)—Researchers at UCLA's Jonsson Comprehensive Cancer Center have discovered the mechanism by which an experimental drug known as GCS-100 removes from lymphoma cells a protein that prevents the cells from ...
Cancer
Oct 15, 2012 |
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Prospective Alzheimer's drug builds new brain cell connections
Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.
Alzheimer's disease & dementia
Oct 11, 2012 |
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Sugar-free approach to treating Kaposi sarcoma
A sugar-loving protein drives the growth of Kaposi sarcoma (KS) tumors, according to a study published on October 1st in The Journal of Experimental Medicine. Interfering with these sugary interactions inhibited growth of Kap ...
Cancer
Oct 01, 2012 |
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Fragile X study offers new drug hope
(Medical Xpress)—An experimental drug can improve sociability in patients with fragile X syndrome and may be helpful as a treatment for autism, according to a study.
Autism spectrum disorders
Sep 24, 2012 |
3 / 5 (1) |
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Experimental drug could help reduce brain damage, improve motor skills after stroke
(Medical Xpress)—A University of Arizona professor is overseeing the manufacture of an experimental drug that could help reduce brain damage after a stroke.
Medical research
Sep 21, 2012 |
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Genetically-engineered preclinical models predict pharmacodynamic response
New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic ...
Cancer
Sep 19, 2012 |
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Experimental diabetes drug could help fight Alzheimer's disease
(Medical Xpress)—A drug designed for diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer's, a study by scientists at the University of Ulster has revealed.
Alzheimer's disease & dementia
Sep 14, 2012 |
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Previously undiscovered cannibis compound could lead to improved epilepsy treatment
(Medical Xpress)—Scientists at the University of Reading have demonstrated for the first time that a previously unstudied chemical in cannabis could lead to more effective treatments for people with epilepsy.
Neuroscience
Sep 13, 2012 |
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Why does Alzheimer's disease affect twice as many women as men?
A group of experts has developed consensus recommendations for future research directions to determine why nearly two-thirds of Americans with Alzheimer's disease (AD) are women. The recommendations are published ...
Alzheimer's disease & dementia
Sep 05, 2012 |
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Possible therapy for tamoxifen resistant breast cancer identified
(Medical Xpress)—A study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) has discovered how tamoxifen-resistant ...
Cancer
Aug 30, 2012 |
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Researchers discover a new therapy that prevents lung cancer growth in mice
Lung cancer is one of the most aggressive types of cancer and the most common cause of death from this disease worldwide. Despite the progress in the molecular biology of lung cancer achieved in recent years, the mechanisms ...
Cancer
Aug 13, 2012 |
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Treating drug resistant cancer through targeted inhibition of sphingosine kinase
Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New ...
Cancer
Aug 09, 2012 |
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Clinical trials start for stroke drug developed by Scripps Research, USC, and ZZ Biotech
Clinical trials start this week for a stroke drug initially created by a team led by scientists at The Scripps Research Institute and the University of Southern California (USC), and further developed by biotech company ZZ ...
Medications
Aug 08, 2012 |
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