News tagged with experimental model


Breakthrough could help sufferers of fatal lung disease

Pioneering research conducted by the University of Sheffield is paving the way for new treatments which could benefit patients suffering from the fatal lung disease pulmonary arterial hypertension (PAH).

Medical research created Oct 15, 2012 | popularity not rated yet | comments 0 | with audio podcast

PET predicts early response to treatment for head and neck cancer patients

Determining the optimal treatment course and predicting outcomes may get easier in the future for patients with head and neck sqaumous cell carcinomas (HNSCCs) with the use of an investigational imaging agent. Research published ...

Cancer created Oct 01, 2012 | popularity 5 / 5 (1) | comments 0

Study explores how brain disruption may foster schizophrenia

(Medical Xpress)—A team led by Yale researchers has used pharmacological neuroimaging and computational modeling to examine large-scale functional organization in the human brain. Their novel approach has ...

Neuroscience created Sep 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Experimental drug could help reduce brain damage, improve motor skills after stroke

(Medical Xpress)—A University of Arizona professor is overseeing the manufacture of an experimental drug that could help reduce brain damage after a stroke.

Medical research created Sep 21, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Genetically-engineered preclinical models predict pharmacodynamic response

New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic ...

Cancer created Sep 19, 2012 | popularity not rated yet | comments 0 | with audio podcast

Previously undiscovered cannibis compound could lead to improved epilepsy treatment

(Medical Xpress)—Scientists at the University of Reading have demonstrated for the first time that a previously unstudied chemical in cannabis could lead to more effective treatments for people with epilepsy.

Neuroscience created Sep 13, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

pH-sensitive liposomal cisplatin improves peritoneal carcinomatosis treatment without side-effects

Scientists at the Oswaldo Cruz Foundation and Federal University of Minas Gerais, led by Dr. Andréa Teixeira-Carvalho and Dr. Mônica Cristina de Oliveira, have developed and characterized a circulating and pH-sensitive ...

Medical research created Aug 27, 2012 | popularity not rated yet | comments 0

Treating drug resistant cancer through targeted inhibition of sphingosine kinase

Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New ...

Cancer created Aug 09, 2012 | popularity not rated yet | comments 0

Clinical trials start for stroke drug developed by Scripps Research, USC, and ZZ Biotech

Clinical trials start this week for a stroke drug initially created by a team led by scientists at The Scripps Research Institute and the University of Southern California (USC), and further developed by biotech company ZZ ...

Medications created Aug 08, 2012 | popularity not rated yet | comments 0

Study identifies receptor's role in regulating obesity, type 2 diabetes

A recent study led by Boston University School of Medicine (BUSM) demonstrates that the A2b-type adenosine receptor, A2bAR, plays a significant role in the regulation of high fat, high cholesterol diet-induced symptoms of ...

Diabetes created Jul 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Research identifies link between Alzheimer's disease and diabetes

(Medical Xpress) -- Researchers from the University of Medicine and Dentistry of New Jersey (UMDNJ), collaborating with scientists from Northwestern University in Illinois, have provided direct experimental evidence that ...

Alzheimer's disease & dementia created Jul 19, 2012 | popularity not rated yet | comments 0 | with audio podcast

An economical, effective and biocompatible gene therapy strategy promotes cardiac repair

Dr Changfa Guo, Professor Chunsheng Wang and their co-investigators from Zhongshan hospital Fudan University, Shanghai, China have established a novel hyperbranched poly(amidoamine) (hPAMAM) nanoparticle based hypoxia regulated ...

Medical research created Jul 06, 2012 | popularity not rated yet | comments 0

Cystic fibrosis makes airways more acidic, reduces bacterial killing

The human airway is a pretty inhospitable place for microbes. There are numerous immune defense mechanisms poised to kill or remove inhaled bacteria before they can cause problems. But cystic fibrosis (CF) disrupts these ...

Medical research created Jul 04, 2012 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

Study shows role of cellular protein in regulation of binge eating

Researchers from Boston University School of Medicine (BUSM) have demonstrated in experimental models that blocking the Sigma-1 receptor, a cellular protein, reduced binge eating and caused binge eaters to eat more slowly. ...

Neuroscience created Jun 20, 2012 | popularity not rated yet | comments 0

Studies show that pancreatic cancer can run but not always hide from the immune system

A pair of recent studies describes how pancreatic cancer cells produce a protein that attracts the body's immune cells and tricks them into helping cancer cells grow. The research, published by Cell Press in the June 12th ...

Cancer created Jun 11, 2012 | popularity not rated yet | comments 0 | with audio podcast