Gastroenterology

Study shows how estrogen protects against fatty liver

New research from Karolinska Institutet shows how estrogen protects against MASLD, a fatty liver disease that has increased dramatically during the current obesity epidemic. The study, published in Molecular Systems Biology, ...

Biomedical technology

Researchers use the eye as a window to study liver health

Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window ...

Neuroscience

New gut-brain circuits found for sugar and fat cravings

Understanding why we overeat unhealthy foods has been a long-standing mystery. While we know food's strong power influences our choices, the precise circuitry in our brains behind this is unclear. The vagus nerve sends internal ...

Medications

Study suggests key to antipsychotic-drug–induced obesity

An increased concentration of the hormone leptin in fat cells is believed to be responsible for weight gain associated with antipsychotic drugs, according to research led by UT Southwestern Medical Center. The study, published ...

Oncology & Cancer

Scientists show reprogrammed fat cells support tumor growth

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the German Cancer Research Center (DKFZ) ...

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Adipose tissue

In histology, adipose tissue or body fat or just fat is loose connective tissue composed of adipocytes. Adipose tissue is derived from lipoblasts. Its main role is to store energy in the form of fat, although it also cushions and insulates the body. Obesity or being overweight in humans and most animals does not depend on body weight but on the amount of body fat—specifically, adipose tissue. Two types of adipose tissue exist: white adipose tissue (WAT) and brown adipose tissue (BAT). Adipose tissue also serves as an important endocrine organ by producing hormones such as leptin, resistin and the cytokine TNFα. The formation of adipose tissue appears to be controlled by the adipose gene. Adipose tissue was first identified by the Swiss naturalist Conrad Gessner in 1551.\

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