Scientists identify Buphenyl as a possible drug for Alzheimer's disease
(Medical Xpress)—Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease. Hyperammonemia is a life-threatening condition that can affect patients at ...
Alzheimer's disease & dementia
Mar 11, 2013 |
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Nanotech'ed RNA drug reduces ovarian cancer tumors by 83 percent
By loading fragile RNA into silicon nanoparticles, researchers from The Methodist Hospital and two other institutions found a new drug delivery system can reduce the size of ovarian tumors by as much as 83 ...
Cancer
Feb 14, 2013 |
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Researchers develop molecular 'calcium sponge' to tackle heart failure
Researchers at the University of Minnesota's Department of Integrative Biology and Physiology and the Lillehei Heart Institute have utilized molecular genetic engineering to optimize heart performance in models of diastolic ...
Cardiology
Feb 10, 2013 |
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Gene therapy cocktail shows promise in long-term clinical trial for rare fatal brain disorder
Results of a clinical trial that began in 2001 show that a gene therapy cocktail conveyed into the brain by a molecular special delivery vehicle may help extend the lives of children with Canavan disease, a rare and fatal ...
Medical research
Dec 19, 2012 |
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Cancer therapy: Nanokey opens tumors to attack
There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart ...
Cancer
Nov 14, 2012 |
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Newly discovered molecule could deliver drugs to treat diseases
(Medical Xpress)—Kansas State University researchers have discovered a molecule that may be capable of delivering drugs inside the body to treat diseases.
Medical research
Sep 24, 2012 |
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An economical, effective and biocompatible gene therapy strategy promotes cardiac repair
Dr Changfa Guo, Professor Chunsheng Wang and their co-investigators from Zhongshan hospital Fudan University, Shanghai, China have established a novel hyperbranched poly(amidoamine) (hPAMAM) nanoparticle based hypoxia regulated ...
Medical research
Jul 06, 2012 |
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Targeted gene therapy enhances treatment for Pompe disease
Gene therapy to replace the protein missing in Pompe disease can be effective if the patient's immune system does not react against the therapy. Targeted delivery of the gene to the liver, instead of throughout the body,suppresses ...
Diseases, Conditions, Syndromes
Jun 25, 2012 |
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Researchers determine 3D structure of adeno-associated virus 9: Aim to boost gene therapy
A team of researchers led by the University of Florida, Gainesville, has determined the precise structure of a virus that has promise as a delivery vehicle for gene therapy. The research appears in the June 2012 issue of ...
Genetics
Jun 21, 2012 |
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Clinical trial for muscular dystrophy demonstrates safety of customized gene therapy
Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, ...
Medical research
Nov 30, 2011 |
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Study could help improve gene therapy for heart disease, cancer
A Loyola University Chicago Stritch School of Medicine study could lead to improved gene therapies for conditions such as heart disease and cancer as well as more effective vaccines for tuberculosis, malaria and other diseases.
Cardiology
Oct 12, 2011 |
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NIH grant for the move toward clinical trials targeting the lysosomal storage disease MPSIIIB
Investigators at Nationwide Children's have received a grant from the National Institutes of Health (NIH) to help move a therapy for MPS IIIB that has been shown effective in mice toward clinical trials in humans.
Medical research
May 25, 2011 |
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Gene therapy success depends on ability to advance viral delivery vectors to commercialization
Many gene therapy strategies designed to deliver a normal copy of a gene to cells carrying a disease-causing genetic mutation rely on a modified virus to transfer the gene product into affected tissues. One ...
Genetics
May 18, 2011 |
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