News tagged with gene expression

Novel RNA-based classification system for colorectal cancer

A novel transcriptome-based classification of colon cancer that improves the current disease stratification based on clinicopathological variables and common DNA markers is presented in a study published in PLOS Medicine this w ...

Cancer created May 21, 2013 | popularity not rated yet | comments 0

Team finds mechanism linking key inflammatory marker to cancer

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

Cancer created May 20, 2013 | popularity not rated yet | comments 0 | with audio podcast

Vicious cycle: Obesity sustained by changes in brain biochemistry

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...

Medical research created May 16, 2013 | popularity 3 / 5 (2) | comments 2 | with audio podcast

Cells must use their brakes moderately for effective speed control

How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published ...

Medical research created May 15, 2013 | popularity 4 / 5 (1) | comments 0

Research finds spontaneous mutations are major cause of congenital heart disease

Every year, thousands of babies are born with severely malformed hearts, disorders known collectively as congenital heart disease. Many of these defects can be repaired though surgery, but researchers don't understand what ...

Cardiology created May 12, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Your immune system: On surveillance in the war against cancer

Predicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach, and new research from Wake Forest Baptist Medical Center is advancing the field when it comes to the most ...

Genetics created May 09, 2013 | popularity not rated yet | comments 0

Researchers identify how cells control calcium influx

(Medical Xpress)—When brain cells are overwhelmed by an influx of too many calcium molecules, they shut down the channels through which these molecules enter the cells. Until now, the "stop" signal mechanism that cells ...

Neuroscience created May 09, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researchers discover possible trigger for spread of head and neck cancer cells

(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell carcinomas and their ...

Cancer created May 08, 2013 | popularity not rated yet | comments 0

Genetic variations associated with susceptibility to bacteria linked to stomach disorders

Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and st ...

Diseases, Conditions, Syndromes created May 07, 2013 | popularity not rated yet | comments 0

Scientists find clues to some inherited heart diseases

(Medical Xpress)—Cornell researchers have uncovered the basic cell biology that helps explain heart defects found in diseases known as laminopathies, a group of some 15 genetic disorders that include forms ...

Medical research created May 07, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study reveals magnitude of variation in gene expression measurements within breast cancers

An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer.

Cancer created May 02, 2013 | popularity not rated yet | comments 0

Breast cancer heterogeneity no barrier to predictive testing, study shows

Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor ...

Cancer created May 02, 2013 | popularity 5 / 5 (1) | comments 0

Microglia derived from patient-specific human-induced pluripotent stem cells

Today, during the 81st American Association of Neurological Surgeons (AANS) Annual Scientific Meeting, researchers announced new findings regarding the development of methods to turn human induced pluripotent stem cells (iPSC) ...

Medical research created May 02, 2013 | popularity not rated yet | comments 0

Study finds why some don't respond to rubella vaccine

Using advanced genetic sequencing technology and analysis, Mayo Clinic vaccine researchers have identified 27 genes that respond in very different ways to the standard rubella vaccine, making the vaccine less effective for ...

Immunology created May 01, 2013 | popularity not rated yet | comments 0

Mouse study provides new clue to staying skinny on a high-fat diet

(Medical Xpress)—The mystery of why some people get fat eating high-fat foods while others can stay skinny on a diet of burgers and chips is closer to being solved.

Diabetes created May 01, 2013 | popularity 3 / 5 (2) | comments 1

Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.

Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

For more information about Gene expression, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: genes , cells , protein , genome , cancer cells