Inflammatory disorders
Inflammatory skin diseases classified at molecular level
In research published online April 15 in Science Immunology, distinct classes of human inflammatory skin disease are defined at the molecular level.
Apr 18, 2022
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News tagged with gene signature
Genetics
Study links genes with function across the human brain
Many psychiatric disorders have genetic causes, but the exact mechanism of how genes influence higher brain function remains a mystery. A new study provides a map linking the genetic signature of functions across the human ...
Mar 25, 2021
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Oncology & Cancer
Scientists identify a gene signature to assess cancer risk in people
In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have ...
Feb 6, 2023
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Oncology & Cancer
Naturally occurring mechanism of cancer drug-resistance may itself be a treatment target
The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs. But Whitehead Institute researchers have found a mechanism underlying this resistance—a ...
Dec 27, 2016
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Oncology & Cancer
Scientists identify link between mitochondria and pancreatic cancer risk
The mitochondria is a key energy-producing component of the human cell that plays an important role in cancer cell metabolism. In a research paper published in PLOS ONE, Dario C. Altieri, M.D., president and chief executive ...
Oct 12, 2022
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Neuroscience
A complex gene program initiates brain changes in response to cocaine
The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion ...
Jul 9, 2020
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Diseases, Conditions, Syndromes
Researchers identify potential diagnostic test for Kawasaki disease
For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed ...
Aug 6, 2018
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Oncology & Cancer
Immune system development linked to leukemia
Scientists have discovered a genetic signature that implicates a key mechanism in the immune system as a driving force for a type of childhood leukaemia.
Jan 12, 2014
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Diseases, Conditions, Syndromes
Blood test could transform tuberculosis diagnosis, treatment in developing countries
A simple blood test that can accurately diagnose active tuberculosis could make it easier and cheaper to control a disease that kills 1.5 million people every year.
Feb 19, 2016
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Oncology & Cancer
Researchers develop model to predict treatment response in gastric cancer
A study by researchers at Mayo Clinic Cancer Center in Florida is validating the use of genomic sequencing to predict the likelihood that patients with gastric cancer will derive benefit from chemotherapy or from immunotherapy. ...
Feb 14, 2022
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