Researchers develop gene therapy that could correct a common form of blindness
A new gene therapy method developed by University of Florida researchers has the potential to treat a common form of blindness that strikes both youngsters and adults. The technique works by replacing a malfunctioning gene ...
Ophthalmology
Jan 23, 2012 |
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Understanding the structure of the TAL effector may be key for targeted gene correction
Researchers at Fred Hutchinson Cancer Research Center have solved the three-dimensional structure of a newly discovered type of gene-targeting protein that has shown to be useful as a DNA-targeting molecule for gene correction, ...
Genetics
Jan 05, 2012 |
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Can nerve growth factor gene therapy prevent diabetic heart disease?
Diabetes is a major risk factor for cardiovascular disease and can reduce blood supply to the heart tissue and damage cardiac cells, resulting in heart failure. New research has investigated if nerve growth factor (NGF) gene ...
Diseases, Conditions, Syndromes
Dec 20, 2011 |
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Novel immuno-gene therapy shows promise for the treatment of rare, deadly form of cancer
(Medical Xpress) -- Researchers at the Perelman School of Medicine at the University of Pennsylvania report promising new results from a small clinical trial using an immune-system-based gene therapy for treating advanced ...
Cancer
Dec 16, 2011 |
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Gene therapy helps patients with hemophilia B
(Medical Xpress) -- An experimental gene therapy technique boosted the production of a vital blood clotting factor in six people with hemophilia B, according to new research supported by the National Institutes of Health. ...
Medical research
Dec 13, 2011 |
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New method boosts blood-clotting for hemophiliacs
Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated ...
Diseases, Conditions, Syndromes
Dec 11, 2011 |
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The newest of the new in gene therapy: 'Tag and target and exchange'
A combination of two techniques promises to improve the efficiency and effectiveness of experimental gene therapies, while also reducing potential side effects says a new research report published in the December 2011 issue ...
Genetics
Nov 30, 2011 |
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Clinical trial for muscular dystrophy demonstrates safety of customized gene therapy
Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, ...
Medical research
Nov 30, 2011 |
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Breast cancer type linked to paternal cancer
The risk of breast cancer is increased by genetic and lifestyle factors such as the inherited BRCA2 gene, age of having first child, or use of hormone replacement therapy (HRT). New research published in BioMed Central's ...
Cancer
Nov 28, 2011 |
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A second 'bad' gene is linked to damaged cell buildup, paralysis in ALS
Following a major Northwestern Medicine breakthrough that identified a common converging point for all forms of amyotrophic lateral sclerosis (ALS and Lou Gehrig's disease), a new finding from the same scientists further ...
Genetics
Nov 21, 2011 |
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Phase I trial begins using gene therapy and bone marrow stem cells in the treatment of brain cancer
University Hospitals (UH) Case Medical Center, Case Western Reserve University School of Medicine and Lentigen Corporation announced today the initiation of a novel Phase I clinical trial of LG631 gene therapy for the protection ...
Cancer
Nov 14, 2011 |
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Tamoxifen resistance -- and how to defeat it
In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because ...
Cancer
Nov 13, 2011 |
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Researchers identify skin cancer genes
(Medical Xpress) -- The genes which contribute to the most frequently occurring life threatening form of skin cancer have been identified for the first time by a research collaboration between the University ...
Cancer
Nov 10, 2011 |
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Study describes first proof of principle for treating rare bone disease
(Medical Xpress) -- Scientists at Penn’s Perelman School of Medicine Center for Research in FOP and Related Disorders have developed a new genetic approach to specifically block the damaged copy of the ...
Genetics
Nov 07, 2011 |
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Gene therapy shows promise as hemophilia treatment in animal studies
For the first time, researchers have combined gene therapy and stem cell transplantation to successfully reverse the severe, crippling bleeding disorder hemophilia A in large animals, opening the door to the development of ...
Medical research
Nov 03, 2011 |
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