Examining function of all genes in the zebrafish genome to benefit human health
Equipped with the zebrafish genome, researchers have designed a method to assay the function of each and every gene and to explore the effects genetic variation has on zebrafish. So far the team has generated one or more ...
Genetics
Apr 17, 2013 |
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Completion of the zebrafish reference genome yields strong comparisons with the human genome
Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart. ...
Genetics
Apr 17, 2013 |
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Discovery of genetic defect that triggers epilepsy
Researchers at the University Department of Neurology at the MedUni Vienna have identified a gene behind an epilepsy syndrome, which could also play an important role in other idiopathic (genetically caused) ...
Neuroscience
Apr 17, 2013 |
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One step closer to understanding biology behind genetic variants linked to blood cell traits
(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute and University of Cambridge have unpicked genetic variants that affect the formation of blood cells. They found that around a third of ...
Genetics
Apr 17, 2013 |
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Recipe for large numbers of stem cells requires only one ingredient
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...
Medical research
Apr 17, 2013 |
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Gene study helps understand pulmonary fibrosis
A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that ...
Diseases, Conditions, Syndromes
Apr 16, 2013 |
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Spread of breast cancer linked to kisspeptins which normally inhibit metastasis
KISS 1 is a metastasis-suppressor gene which helps to prevent the spread of cancers, including melanoma, pancreatic and ovarian cancers to name a few. But new research from Western University's Schulich School of Medicine ...
Cancer
Apr 16, 2013 |
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Vitamin A could prevent the spread of prostate cancer
(Medical Xpress)—Vitamin A could help treat and prevent the spread of prostate cancer, according to research published today (Monday, April 15th) in Oncogenesis.
Cancer
Apr 16, 2013 |
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Haiti cholera mutations could lead to more severe disease: Strain is evolving to be more like virulent 1800s cholera
The cholera strain that transferred to Haiti in 2010 has multiple toxin gene mutations that may account for the severity of disease and is evolving to be more like an 1800s version of cholera, reports a new Northwestern Medicine ...
Diseases, Conditions, Syndromes
Apr 16, 2013 |
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Gene signature can predict who will survive chemotherapy
An eight gene 'signature' can predict length of relapse-free survival after chemotherapy, finds new research in Biomed Central's open access journal BMC Medicine.
Cancer
Apr 15, 2013 |
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Autism model in mice linked with genetics
For the first time, researchers have linked autism in a mouse model of the disease with abnormalities in specific regions of the animals' chromosomes. The regions contain genes associated with aberrant brain development and ...
Autism spectrum disorders
Apr 15, 2013 |
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Science of genome-sequencing marks 10 years
A decade after completion of the Human Genome Project on April 14, 2003, a top official of the National Institutes of Health surveyed the rarefied view from that mountaintop:
Genetics
Apr 15, 2013 |
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Gene-expression signature may signify risk for recurrence, metastasis in prostate cancer
A team led by Massachusetts General Hospital (MGH) researchers has identified a genetic signature that appears to reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer. If confirmed ...
Cancer
Apr 15, 2013 |
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Cancer cell metabolism kills
Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...
Cancer
Apr 15, 2013 |
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Patenting genes: Justices tackle big health issue (Update 2)
The Supreme Court seemed worried Monday about the idea of companies patenting human genes in a case that could profoundly reshape the multibillion-dollar biomedical industry and U.S. research in the fight ...
Genetics
Apr 15, 2013 |
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