News tagged with genetic alteration


Researchers a step closer to controlling inflammation in MS

(Medical Xpress)—A University of Adelaide researcher has published results that suggest a possible new mechanism to control multiple sclerosis (MS).

Medical research created Oct 04, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

First large scale trial of whole-genome cancer testing for clinical decision-making reported

For the first time, researchers have conducted a large trial in which they tested the entire genome of individual breast cancers to help personalize treatment. They released their findings at the ESMO 2012 Congress of the ...

Cancer created Oct 01, 2012 | popularity not rated yet | comments 0

Stemming the spread of cancer

Okayama University's Masaharu Seno and colleagues have demonstrated in vitro the development of cancer stem cells (CSCs) from a type of normal stem cell exposed to their hypothetical microenvironment of a ...

Cancer created Sep 21, 2012 | popularity not rated yet | comments 0

In lung cancer, smokers have 10 times more genetic damage than never-smokers

Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine ...

Cancer created Sep 13, 2012 | popularity 5 / 5 (2) | comments 0

ENCODE project: Researchers catalogue functional elements of the genome

Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the "switches" that control them. Characterizing these switches is one of many goals of the ENCODE project ...

Genetics created Sep 05, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Team creates a unique mouse model for the study of aplastic anaemia

Aplastic anaemia is characterised by a reduction in the number of the bone marrow cells that go on to form the different cell types present in blood (essentially red blood cells, white blood cells and platelets). In most ...

Medical research created Aug 29, 2012 | popularity not rated yet | comments 0

Blood test could guide treatment for kidney cancer

A common enzyme that is easily detected in blood may predict how well patients with advanced kidney cancer will respond to a specific treatment, according to doctors at Duke Cancer Institute.

Cancer created Aug 13, 2012 | popularity not rated yet | comments 0

Existing drugs offer new treatment options for high-risk childhood leukemia subtype

Scientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.

Cancer created Aug 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Genetic variant is linked to obesity and insulin resistance

A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented ...

Genetics created Jun 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Gene sequencing project identifies potential drug targets in common childhood brain tumor

Researchers studying the genetic roots of the most common malignant childhood brain tumor have discovered missteps in three of the four subtypes of the cancer that involve genes already targeted for drug development.

Cancer created Jun 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers create powerful new method to analyze genetic data

University of Texas Medical Branch at Galveston researchers have developed a powerful visual analytical approach to explore genetic data, enabling scientists to identify novel patterns of information that could be crucial ...

Genetics created Jun 12, 2012 | popularity not rated yet | comments 1 | with audio podcast

Distinct molecular subtype of prostate cancer identified

A collaborative expedition into the deep genetics of prostate cancer has uncovered a distinct subtype of the disease, one that appears to account for up to 15 percent of all cases, say researchers at Weill Cornell Medical ...

Genetics created May 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Molecular subtypes and genetic alterations may determine response to lung cancer therapy

Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. But scientists are finding that in many types of cancer the molecular ...

Cancer created May 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists find that chromosomal abnormalities are associated with aging and cancer

(Medical Xpress) -- Two new studies have found that large structural abnormalities in chromosomes, some of which have been associated with increased risk of cancer, can be detected in a small fraction of people without a ...

Genetics created May 08, 2012 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Higher maternal age predicts risk of autism

In a study published in the May 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry, led by Mr. Sven Sandin, of the Karolinska Institutet, Sweden and King's College London, researchers analyz ...

Autism spectrum disorders created Apr 26, 2012 | popularity not rated yet | comments 0