News tagged with genetic alteration

New evidence for genetic basis of autism found

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. ...

Oct 03, 2011
popularity 4.3 / 5 (9) | comments 6 | with audio podcast

New view of tumors' evolution

Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as "drivers," help spur cells to grow out of control, while others ("passengers") are merely along ...

Mar 13, 2014
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Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with ...

Sep 20, 2013
popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Clinical trials for cancer, one patient at a time

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time. The patient's tumor is "reverse ...

Jul 15, 2013
popularity 3.7 / 5 (3) | comments 1 | with audio podcast

Study unmasks regulator of healthy life span

A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and ...

Dec 17, 2012
popularity 5 / 5 (2) | comments 0 | with audio podcast