New drug, Vemurafenib, doubles survival of metastatic melanoma patients
A report published this week in the New England Journal of Medicine shows that the 50 percent of metastatic melanoma patients with a specific genetic mutation benefit from the drug Vemurafenib – increasing median surviv ...
Cancer
Mar 01, 2012 |
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Tailoring drugs to fit a patient’s genetic predisposition
Drugs are not equally effective on all patients. A treatment that is dramatically effective on some patients can be ineffective on others. Drugs can also have serious side effects; in the worst case, a drug ...
Medications
Feb 27, 2012 |
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Family history -- a significant way to improve cardiovascular disease risk assessment
A new study by researchers at The University of Nottingham has proved that assessing family medical history is a significant tool in helping GPs spot patients at high risk of heart disease and its widespread use could save ...
Cardiology
Feb 22, 2012 |
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Research identifies potential antibiotic alternative to treat infection without resistance
(Medical Xpress) -- Researchers at the University of Michigan have found a potential alternative to conventional antibiotics that could fight infection with a reduced risk of antibiotic resistance.
Medical research
Feb 20, 2012 |
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New HIV-vaccine tested on people
Scientists from the Antwerp Institute of Tropical Medicine, Antwerp University Hospital and Antwerp University have tested a new 'therapeutic vaccine' against HIV on volunteers. The participants were so to say vaccinated ...
HIV & AIDS
Feb 13, 2012 |
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Gene mutation discovery sparks hope for effective endometriosis screening
Researchers at Yale School of Medicine have, for the first time, described the genetic basis of endometriosis, a condition affecting millions of women that is marked by chronic pelvic pain and infertility. ...
Genetics
Feb 06, 2012 |
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Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Cancer
Jan 30, 2012 |
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Genetic regulation of metabolomic biomarkers -- paths to cardiovascular diseases and type 2 diabetes
In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that ...
Diabetes
Jan 29, 2012 |
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Study pinpoints genetic variation that raises a risk linked to bisphosphonates
Researchers at the Columbia University College of Dental Medicine have identified a genetic variation that raises the risk of developing serious necrotic jaw bone lesions in patients who take bisphosphonates, a common class ...
Cancer
Jan 27, 2012 |
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Rare kidney disease shows how salt, potassium levels are moderated
High blood pressure (hypertension) is a principal risk factor for heart disease and affects 1 billion people. At least half of them are estimated to be salt-sensitive; their blood pressure rises with sodium intake. New research ...
Medical research
Jan 23, 2012 |
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Inflammatory mediator promotes colorectal cancer by stifling protective genes
Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today ...
Inflammatory disorders
Jan 22, 2012 |
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New research suggests birth weight plays a role in autism spectrum disorder
Although the genetic basis of autism is now well established, a growing body of research also suggests that environmental factors may play a role in this serious developmental disorder affecting nearly one in 100 children. ...
Autism spectrum disorders
Jan 19, 2012 |
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Genetic mutation leads to cold allergy, immune deficiency and autoimmunity
Investigators at the National Institutes of Health have identified a genetic mutation in three unrelated families that causes a rare immune disorder characterized by excessive and impaired immune function. Symptoms of this ...
Medical research
Jan 11, 2012 |
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New research finds trigger for breast cancer spread
Research led by Shyamal Desai, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has discovered a key change in the body's defense system that increases the potential ...
Cancer
Jan 03, 2012 |
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Severe congenital disorder successfully treated in a mouse model for the first time
Using a mouse model, Heidelberg University Hospital researchers have for the first time successfully treated a severe congenital disorder in which sugar metabolism is disturbed. The team headed by Prof. Christian Korner, ...
Genetics
Dec 22, 2011 |
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