News tagged with glutamate receptor


Researchers unravel molecular roots of Down syndrome

Sanford-Burnham researchers discover that the extra chromosome inherited in Down syndrome impairs learning and memory because it leads to low levels of SNX27 protein in the brain.

Medical research created Mar 24, 2013 | popularity 4.4 / 5 (9) | comments 0 | with audio podcast

The mysterious GRIN3A and the cause of schizophrenia

Since the 1960s, psychiatrists have been hunting for substances made by the body that might accumulate in abnormally high levels to produce the symptoms associated with schizophrenia. In particular, there was a search for ...

Psychology & Psychiatry created Mar 14, 2013 | popularity 4 / 5 (1) | comments 0

Group Therapy: New approach to psychosis treatment could target multiple nervous system receptors

Antipsychotic drugs, used in the treatment of psychotic disorders involving severe delusions and hallucinations, have been studied for more than 70 years. Currently available antipsychotic drugs, however, only alleviate certain ...

Psychology & Psychiatry created Feb 01, 2013 | popularity not rated yet | comments 1

Scientists learn more about how inhibitory brain cells get excited

Scientists have found an early step in how the brain's inhibitory cells get excited.

Neuroscience created Jan 30, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Experimental agent briefly eases depression rapidly in test: Works in brain like ketamine, with fewer side effects

(Medical Xpress)—A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, ...

Psychology & Psychiatry created Dec 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Next-generation treatments for Fragile X syndrome

A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Ita ...

Psychology & Psychiatry created Nov 29, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

CAMH protein discovery may lead to new treatment to prevent smoking relapse

Scientists at the Centre for Addiction and Mental Health (CAMH) have identified a potential new approach to preventing smoking relapse, which occurs frequently in smokers who attempt to quit, despite current treatments.

Health created Oct 22, 2012 | popularity 5 / 5 (2) | comments 0

Excitotoxicity and nerve cell death

Neural excitotoxicity can be involved in spinal cord injury, traumatic hearing loss and Alzheimer's. The Stressprotect project has gathered data on this often devastating phenomenon at biochemical, genomic ...

Medical research created Sep 25, 2012 | popularity not rated yet | comments 0

Scientists reverse disorder of neuronal circuits in autism

People with autism suffer from a pervasive developmental disorder of the brain that becomes evident in early childhood. Peter Scheiffele and Kaspar Vogt, Professors at the Biozentrum of the University of ...

Autism spectrum disorders created Sep 14, 2012 | popularity 4.9 / 5 (11) | comments 1 | with audio podcast

Agent reduces autism-like behaviors in mice

National Institutes of Health researchers have reversed behaviors in mice resembling two of the three core symptoms of autism spectrum disorders (ASD). An experimental compound, called GRN-529, increased social ...

Autism spectrum disorders created Apr 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

New medication offers hope to patients with frequent, uncontrollable seizures

A new type of anti-epilepsy medication that selectively targets proteins in the brain that control excitability may significantly reduce seizure frequency in people whose recurrent seizures have been resistant to even the ...

Neuroscience created Apr 18, 2012 | popularity 5 / 5 (1) | comments 0

What does chronic stress in adolescence mean at the molecular level?

Chronic stress has a more powerful effect on the brain during adolescence than in adulthood and now there's proof at the molecular level, according to findings published in Neuron by University at Buffalo researchers.

Neuroscience created Mar 07, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Researchers uncover steps in synapse building, pruning

Like a gardener who stakes some plants and weeds out others, the brain is constantly building networks of synapses, while pruning out redundant or unneeded synapses. Researchers at The Jackson Laboratory led by Assistant ...

Neuroscience created Nov 16, 2011 | popularity not rated yet | comments 0 | with audio podcast

The architects of the brain: Scientists decipher the role of calcium signals

German neurobiologists have found that certain receptors for the neurotransmitter glutamate determine the architecture of nerve cells in the developing brain. Individual receptor variants lead to especially long and branched ...

Neuroscience created Oct 26, 2011 | popularity 5 / 5 (3) | comments 0

New drug target for Alzheimer's, stroke discovered

A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for Alzheimer's and other neurodegenerative ...

Alzheimer's disease & dementia created Oct 11, 2011 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast