Cells predict onset of graft-versus-host disease in men receiving BMTs from female donors
Stanford University School of Medicine investigators have identified a clutch of cells that—if seen in a male patient's blood after receiving a brand-new immune system in the form of a bone-marrow transplant from a female ...
Medical research
Feb 04, 2013 |
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Landmark study in blood stem cell transplant
(Medical Xpress)—Before all the excitement about embryonic stem cells, doctors were using hematopoetic – that is, blood-forming—stem cells. Hematopoetic stem cells can replenish all the types of cells in the blood, ...
Medical research
Jan 04, 2013 |
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Genetically engineered bacteria could help in Crohn's and colitis
(Medical Xpress)—A new study in mice has shown that genetically engineered bacteria can protect against inflammatory bowel disease (IBD), which includes a host of conditions including ulcerative colitis and Crohn's disease.
Medical research
Nov 02, 2012 |
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Leading bone marrow transplant expert recommends significant change to current practice
One of the world's leading bone marrow transplant experts is recommending a significant change to current transplant practice for patients who need marrow or adult stem cells from an unrelated donor to treat hematologic malignancies. ...
Other
Oct 17, 2012 |
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Deadly complication of stem cell transplants reduced in mice
(Medical Xpress)—Studying leukemia in mice, researchers at Washington University School of Medicine in St. Louis have reduced a life-threatening complication of stem cell transplants, the only curative treatment when leukemia ...
Medical research
Sep 27, 2012 |
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New genetic clues to why most bone marrow transplant patients develop graft-versus-host disease
A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors ...
Medical research
Sep 04, 2012 |
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Bortezomib beneficial in graft-versus-host disease prophylaxis
(HealthDay) -- Patients with hematologic malignancies undergoing an HLA-mismatched unrelated donor (MMUD) reduced-intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT) may benefit from ...
Cancer
Aug 08, 2012 |
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New discovery may lead to effective prevention and treatment of graft-versus-host disease
A new discovery in mice may lead to new treatments that could make bone marrow transplants more likely to succeed and to be significantly less dangerous. According to new research findings published in the Journal of Leukocyte Bi ...
Diseases, Conditions, Syndromes
Apr 01, 2012 |
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Mini-molecule governs severity of acute graft vs. host disease, study finds
Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant.
Cancer
Mar 12, 2012 |
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