Genetics
How pathogenic gene variants lead to heart failure
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports in Science.
Aug 4, 2022
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News tagged with heart muscle tissue
Medical research
New treatment could benefit up to 45 percent of patients with Duchenne muscular dystrophy
Up to 45% of patients with the most common inherited neuromuscular disease could benefit from a new "cocktail" drug being developed at the University of Alberta, according to research published this week in the Proceedings ...
Feb 23, 2022
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161
Cardiology
Restoring heart elasticity in a heart failure model
Patients with heart failure often have shortness of breath and become fatigued quickly. They frequently suffer from water retention, heart palpitations, and dizziness. The condition can be triggered by a combination of elevated ...
Dec 1, 2021
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Cardiology
Finding inspiration to rebuild human heart muscle
Advances in cardiac tissue engineering offer hope for an array of useful applications, from heart repair to disease modeling. As part of active, ongoing research related to bioengineering functional human organs, Adam Feinberg ...
Aug 16, 2021
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591
Cardiology
Hydrogel injection may change the way the heart muscle heals after a heart attack
Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel that could help repair and prevent ...
Feb 19, 2021
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174
Cardiology
Researchers unravel the healing mechanisms of extracellular vesicles
Extracellular vesicles (EVs)—nanometer sized messengers that travel between cells to deliver cues and cargo—are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative ...
Oct 15, 2020
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51
Cardiology
Spectroscopy approach poised to improve treatment for serious heart arrhythmia
Researchers have demonstrated that a new mapping approach based on near infrared spectroscopy can distinguish between fat and muscle tissue in the heart. This distinction is critical when using radiofrequency ablation to ...
Jul 8, 2020
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167
Cardiology
Researchers identify possible drug target for deadly heart condition
A genetic mutation linked to dilated cardiomyopathy, a dangerous enlargement of the heart's main pumping chamber, activates a biological pathway normally turned off in healthy adult hearts, according to a study by researchers ...
Jul 17, 2019
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Cardiology
'Training gym' for lab-grown heart cells: Engineering researchers design new platform
Heart muscle cells need exercise—even when they grow outside the human body. A new device designed by U of T Engineering researchers uses a rigorous training regimen to grow small amounts of cardiac tissue and measure how ...
Jan 24, 2019
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20
Cardiology
A sobering conclusion: Adult hearts contain no stem cells
A detailed cell-by-cell map of all dividing cells in the adult murine heart before and after myocardial infarction was created using advanced molecular and genetic technologies in a combined research effort led by Hans Clevers ...
Dec 3, 2018
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