Identification of mutations common to half of all liver cancers provides leads for new therapeutics
Liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-associated deaths. Yet even for such a frequent and deadly disease, the pathogenesis of this cancer remains obscure. ...
Cancer
Nov 16, 2012 |
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Breast cancer recurrence defined by hormone receptor status
Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research shows ...
Cancer
Oct 01, 2012 |
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Recent findings hold new implications for the pathogenesis of myotonic dystrophy
An important breakthrough could help in the fight against myotonic dystrophy. The discovery, recently published in the prestigious scientific journal Cell, results from an international collaboration between researchers at the ...
Medical research
Sep 12, 2012 |
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Prevalence of TB, hepatitis C, HIV high among homeless
(HealthDay) -- The global prevalence of tuberculosis, hepatitis C virus infection, and HIV is high among homeless people, although significant heterogeneity is seen in prevalence estimates, according to a ...
Diseases, Conditions, Syndromes
Aug 20, 2012 |
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Mechanisms of acquired chemoresistance in ovarian cancer identified
The presence of multiple ovarian cancer genomes in an individual patient and the absence or downregulation of the gene LRP1B are associated with the development of chemoresistance in women with the high-grade serous cancer ...
Cancer
Aug 15, 2012 |
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Coronary rehabilitation programs in Europe are underused
Large proportions of European coronary patients are not benefitting from cardiac rehabilitation services, according to results of the third EUROASPIRE survey published today in the European Journal of Preventive Cardiology.(1) Yet de ...
Cardiology
Jun 19, 2012 |
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Researchers identify need to sample multiple tumor zones in breast cancer
Certain short strands of RNA, known as microRNAs (miRNAs), have been linked to the progression and metastasis of breast cancer and may provide information about prognosis. However, studies of miRNA expression profiles often ...
Cancer
Jun 15, 2012 |
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Tiny implanted coil improves lung function in patients with severe emphysema
A tiny, resilient metal wire designed to gather and compress diseased lung tissue may offer relief to patients with severe heterogeneous emphysema, a subtype of the disease that involves specific, usually isolated areas of ...
Diseases, Conditions, Syndromes
May 23, 2012 |
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Oral zinc may lessen common cold symptoms but adverse effects are common
Oral zinc treatments may shorten the duration of symptoms of the common cold in adults, although adverse effects are common, according to a study published in CMAJ (Canadian Medical Association Journal).
Medications
May 07, 2012 |
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Recent improvement in 3D ECHO accuracy for LV mass
(HealthDay) -- In the past decade there has been an improvement in the accuracy of three-dimensional echocardiography (3DE) for measurement of left ventricular (LV) mass, according to a meta-analysis published ...
Cardiology
May 03, 2012 |
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Six developmental trajectories ID'd in children with autism
(HealthDay) -- Six longitudinal developmental trajectories have been identified among children with autism, with significant heterogeneity seen in developmental pathways within these trajectories, according ...
Autism spectrum disorders
Apr 02, 2012 |
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Intratumor heterogeneity seen in renal carcinomas
(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...
Cancer
Mar 08, 2012 |
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Metabolic profiles essential for personalizing cancer therapy
One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism shows that one metabolism-targeted cancer therapy will not fit all. That means that m ...
Cancer
Feb 07, 2012 |
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Apixaban superior to warfarin for preventing stroke, reducing bleeding and saving lives
A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation. Moreover, apixaban results in ...
Medical research
Aug 28, 2011 |
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It's simple: increasing complexity of models does not necessarily increase their accuracy
Mathematical modeling of infectious diseases is an important tool in the understanding and prediction of epidemics. Knowledge of social interactions is used to understand how infectious diseases spread through populations ...
Medical research
Jul 19, 2011 |
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