Immunology

Enzyme's alter ego helps activate the immune system

Already known to cut proteins, the enzyme SPPL3 turns out to have additional talents, according to a new study from Johns Hopkins. In its newly discovered role, SPPL3 works without cutting proteins to activate T cells, the ...

HIV & AIDS

Occasional heroin use may worsen HIV infection

Researchers at Yale and Boston University and their Russian collaborators have found that occasional heroin use by HIV-positive patients may be particularly harmful to the immune system and worsens HIV disease, compared to ...

Inflammatory disorders

New insight into risk of Ankylosing Spondylitis

Scientists at the University of Southampton have discovered variations in an enzyme belonging to the immune system that leaves individuals susceptible to Ankylosing Spondylitis.

Immunology

How age alters our immune response to bereavement

Young people have a more robust immune response to the loss of a loved one, according to new research from the University of Birmingham, providing insight into how different generations cope with loss.

Oncology & Cancer

Cancer immunotherapy on the cusp

Glass crystals with thread-like filaments floating inside sit in the offices of two prominent immunologists. The clear blocks encase models of the structure of PD-1/PD-L1, a receptor-ligand pair that rides on the surface ...

Alzheimer's disease & dementia

Looking for origins of Alzheimer's disease to find a treatment

Six or so years ago, Frank Longo, MD, PhD, Stanford's chair of neurology and neurological sciences, was optimistic that a treatment for Alzheimer's disease was on its way. More than a decade earlier, pharmaceutical companies ...

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