Immunology

CRISPR screen identifies new anti-inflammatory drug target

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...

Immunology

Novel immunotherapy boosts long-term stroke recovery in mice

Specialized immune cells that accumulate in the brain in the days and weeks after a stroke promote neural functions in mice, pointing to a potential immunotherapy that may boost recovery after the acute injury is over, University ...

Medical research

Mitochondria could boost immunotherapy effectiveness

Boosting mitochondrial function in a subpopulation of T cells could make cancer immunotherapy more effective, according to a recent study published in the Proceedings of the National Academy of Sciences (PNAS).

Oncology & Cancer

Living macrophage-based drug promotes antitumor immunotherapy

Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of efficacy and safety, such as huge ...

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