Medical research

Probing innate immunity, cGAS protein, and our own damaged DNA

The protein cGAS plays an essential role in cellular innate immunity by detecting the DNA of invading pathogens such as bacteria and viruses, or our own damaged and mislocalized DNA. Activation of the cGAS-STING signaling ...

Health

Celiac disease linked to common chemical pollutants

Elevated blood levels of toxic chemicals found in pesticides, nonstick cookware, and fire retardants have been tied to an increased risk for celiac disease in young people, new research shows.

Autism spectrum disorders

Autism in males linked to defect in brain immune cells, microglia

Many cases of autism spectrum disorders (ASDs) may result from problems in immune cells that normally work to trim back unneeded brain connections in early life, suggests a new study led by scientists at Scripps Research.

Arthritis & Rheumatism

Is autoimmunity on the rise?

A study published in Arthritis & Rheumatology provides evidence that the prevalence of autoimmunity—when the immune system goes awry and attacks the body itself—has increased in the United States in recent years.

Immunology

Scientists discover new 'Jekyll and Hyde' immune cell

Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with "Jekyll and Hyde properties". These cells play a key protective role in immunity to infection but—if unregulated—also mediate ...

Medications

The danger behind certain biologics

Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, ...

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