A new study has identified how blocking a special set of molecules on the surface of T cells can suppress the heart's immune response – responsible for transplant rejection and autoimmune diseases such as myocarditis – ...
Jun 17, 2015
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People who are treated with TNF-α inhibitors for their autoimmune disease such as Crohn's disease or rheumatoid arthritis lose their vaccination protection significantly earlier than average. The mechanism underlying the ...
Sep 6, 2023
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Currently, people receiving organ transplants must take drugs to suppress the inflammatory immune response that leads to rejection. Even so, almost all recipients eventually lose their transplant. A new approach, which maintains ...
Jul 9, 2018
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Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.
May 18, 2016
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The world's first double-leg transplant patient has had both limbs amputated after an unrelated illness forced him to stop taking anti-rejection drugs, the Spanish hospital that carried out the operation said Tuesday.
Jun 11, 2013
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(HealthDay)—For patients undergoing living kidney transplants, persistent mixed chimerism can be achieved to allow complete or partial withdrawal of immunosuppressive drugs, according to a study published in the Jan. 29 ...
Jan 30, 2020
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Normal cells have a complex system of checks and balances that regulate cell division. In cancer, the balance is tipped in favor of cell proliferation. This imbalance arises from increased levels or activity of oncoproteins ...
Apr 29, 2019
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The first woman ever to receive a uterus from a deceased donor, is two-weeks pregnant following a successful embryo transplant, her doctors said on Friday.
Apr 12, 2013
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A research team led by Professor Jun Takahashi and Assistant Professor Asuka Morizane at the Center for iPS Cell Research and Application (CiRA) at Kyoto University, Japan, has carried out a study to compare the impact of ...
Sep 26, 2013
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Long-term survival rates of kidney transplant patients in the U.S. have increased over the last three decades, but there are opportunities to further improve these outcomes, according to a review article published today in ...
Aug 19, 2021
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