Diseases, Conditions, Syndromes

Another tantalizing step closer to a universal flu vaccine

Development of a universal flu vaccine has been a long-sought goal, and as flu scientists begin to see light at the end of a decades-long tunnel, encouraging data have emerged on an experimental shot. It appears effective ...

Medical research

Mapping the structure of the influenza A virus genome

A team of researchers from the U.K., Australia and the U.S. has mapped the structure of the influenza A virus genome. In their paper published in the journal Nature Microbiology, the group describes their genetic analysis ...

Diseases, Conditions, Syndromes

Four-in-one antibody used to fight flu shows promise in mice

A large international team of researchers has developed a four-in-one antibody approach to fighting influenza infections. In their paper published in the journal Science, the group describes the development of the antibody ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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