News tagged with insulin resistance

Gut microbe battles obesity

(Medical Xpress)—Akkermansia muciniphila is one of the many microbes that live in our intestines. This bacterium, which feeds on the intestine's mucus lining, comprises between 3 and 5 percent of the gut microbes of hea ...

Medical research created May 14, 2013 | popularity 4.8 / 5 (11) | comments 0 | with audio podcast report

Study: Most-used diabetes drug works in different way than previously thought

A team, led by senior author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Medicine, with the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University ...

Diabetes created Jan 06, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Mouse study offers clues to obesity-diabetes link

(HealthDay)—Obesity and type 2 diabetes are clearly intertwined, but researchers say they've found a way to weaken the connection between the two—at least in mice.

Medical research created Dec 06, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Single gene cause of insulin sensitivity may offer insight for treating diabetes

(Medical Xpress)—The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.

Diabetes created Sep 12, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Neutrophils: White blood cells mediate insulin resistance

Researchers at the University of California, San Diego School of Medicine say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays ...

Medical research created Aug 05, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Protective gene in fat cells may lead to therapeutic for Type 2 diabetes

In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes. The results may lead to a ...

Medical research created Apr 01, 2012 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Study offers insight to how fructose causes obesity, metabolic syndrome

A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes.

Medical research created Feb 27, 2012 | popularity 4.9 / 5 (11) | comments 1 | with audio podcast

Diabetes may start in the intestines, research suggests

Scientists at Washington University School of Medicine in St. Louis have made a surprising discovery about the origin of diabetes. Their research suggests that problems controlling blood sugar — the hallmark ...

Diabetes created Feb 15, 2012 | popularity 4.1 / 5 (16) | comments 4 | with audio podcast

Discovery of insulin switches in pancreas could lead to new diabetes drugs

Researchers at the Salk Institute have discovered how a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin.

Medical research created Sep 26, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Treatment of sleep apnea improves glucose levels in prediabetes

Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in ...

Sleep apnea created 21 hours ago | popularity not rated yet | comments 0 | with audio podcast

Free fatty acids linked to cardiac risk in late adulthood

(HealthDay)—Blood levels of free fatty acids are associated with insulin resistance during young adulthood and cardiovascular risk factors in later adulthood, according to a study published online May 13 ...

Cardiology created May 17, 2013 | popularity not rated yet | comments 0 | with audio podcast

Discovery of new hormone opens doors to new type 2 diabetes treatments

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...

Diabetes created May 07, 2013 | popularity 4.6 / 5 (8) | comments 1 | with audio podcast

Co-Q10 deficiency may relate to concern with statin drugs, higher risk of diabetes

(Medical Xpress)—A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes.

Diseases, Conditions, Syndromes created Apr 10, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Adding intestinal enzyme to diets of mice appears to prevent, treat metabolic syndrome

Feeding an intestinal enzyme to mice kept on a high-fat diet appears to prevent the development of metabolic syndrome – a group of symptoms associated with type 2 diabetes, cardiovascular disease and fatty liver – and ...

Medical research created Apr 08, 2013 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Key link between obesity and type 2 diabetes discovered

(Medical Xpress)—New research published in the journal Cell Metabolism has identified a key mechanism in the immune system involved in the development of obesity-linked type 2 diabetes. The findings open u ...

Medical research created Apr 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Insulin resistance

Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.

For more information about Insulin resistance, read the full article at Wikipedia.
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