CU Cancer Center opens phase I clinical trial of anti-cancer stem cell agent OMP-54F28
The University of Colorado Cancer Center, together with other participating academic medical centers, recently opened a phase I human clinical trial of the drug OMP-54F28 in patients with advanced solid tumor cancers. OMP-54F28, ...
Cancer
Oct 03, 2012 |
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Researchers harness the immune system to improve stem cell transplant outcomes
A novel therapy in the early stages of development at Virginia Commonwealth University Massey Cancer Center shows promise in providing lasting protection against the progression of multiple myeloma following a stem cell transplant ...
Immunology
Oct 01, 2012 |
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NIH launches trial for rare degenerative muscle disease treatment
Researchers have launched a clinical trial to evaluate the drug candidate DEX-M74 as a treatment for a rare degenerative muscle disease, hereditary inclusion body myopathy (HIBM). National Institutes of Health scientists ...
Medical research
Sep 24, 2012 |
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BRCA1 or BRCA2 mutation research may offer treatment option to certain patients
(Medical Xpress)—Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an ...
Cancer
Sep 20, 2012 |
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Toxic protein build-up in blood shines light on Huntington's disease
A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today ...
Neuroscience
Sep 17, 2012 |
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Ovarian cancer cells hijack surrounding tissues to enhance tumor growth
Tumor growth is dependent on interactions between cancer cells and adjacent normal tissue, or stroma. Stromal cells can stimulate the growth of tumor cells; however it is unclear if tumor cells can influence the stroma.
Cancer
Sep 04, 2012 |
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U of T and SickKids first to grow lung cells using stem cell technology
Researchers at the University of Toronto and the Hospital for Sick Children (SickKids) are paving the way towards individualized medicine for patients with cystic fibrosis.
Medical research
Aug 29, 2012 |
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Study identifies potential new class of drug for treating ulcerative colitis
An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University ...
Diseases, Conditions, Syndromes
Aug 15, 2012 |
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FDA approves drug to treat diabetic macular edema
The U.S. Food and Drug Administration today announced its approval of Lucentis (ranibizumab injection) for the treatment of diabetic macular edema, or DME, an eye condition in people with diabetes that causes blurred vision, ...
Medications
Aug 13, 2012 |
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In pilot study, a peptide controls blood sugar in people with congenital hyperinsulinism
A pilot study in adolescents and adults has found that an investigational drug shows promise as the first potential medical treatment for children with the severest type of congenital hyperinsulinism, a rare but potentially ...
Diabetes
Aug 01, 2012 |
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Alzheimer's drug shows promise in early trial
(HealthDay News) -- Researchers say an investigational drug helped improve memory, language, attention and other mental skills in people with early Alzheimer's disease.
Alzheimer's disease & dementia
Jul 18, 2012 |
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Cell differentiation as a novel strategy for the treatment of an aggressive type of skin cancer
Skin squamous cell carcinoma (SCC) is a subtype of very aggressive skin cancers that usually develops in sunexposed body regions, but can also affect a large number of organs such as the bladder, esophagus, lungs etc. However, ...
Cancer
Jul 09, 2012 |
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New trial drug a 'Trojan Horse' attacking pancreatic cancer
An investigational drug that acts like a Trojan Horse to deliver cancer killing agents for pancreatic cancer is being studied at the Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare ...
Cancer
Jun 14, 2012 |
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The challenges and opportunities of clinical trials in developing countries
Conducting more clinical trials in developing countries is of benefit because these populations are underrepresented in research, but doing trials in resource poor settings has many challenges. Research sites in developing ...
Other
Jun 12, 2012 |
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Investigational diabetes drug may have fewer side effects
Drugs for type 2 diabetes can contribute to weight gain, bone fractures and cardiovascular problems, but in mice, an investigational drug appears to improve insulin sensitivity without those troublesome side ...
Medical research
Jun 04, 2012 |
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