Certain types of early-onset epilepsy are caused by previously unknown mutations of a potassium channel gene, KCNA2. The mutations disrupt the electrical balance in the brain in two ways. In some patients, the flow of potassium ...
Mar 11, 2015
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(Medical Xpress) -- Research groups at the University of Cambridge and the Instituto de Neurociencias, in Spain, have discovered a new and unexpected mechanism by which cold sensation is regulated, and opens up the possibility ...
Jul 2, 2012
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Researchers interested in the treatment of schizophrenia and dementia have clarified how antipsychotic drugs that target a complex of two receptors at the surface of cells in the brain work, according to a new study published ...
Nov 23, 2011
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The neuromuscular junction—where nerves and muscle fibers meet—is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of progressive neuromuscular ...
Jan 6, 2022
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Glutamate receptors in the brain called AMPARs are critical for synaptic plasticity, learning and memory. Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, ...
Dec 9, 2019
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Researchers at CNRS, Université Côte d'Azur and Inserm have demonstrated a new mechanism related to the onset of migraine. They found how a mutation that causes dysfunction in a protein which inhibits neuronal electrical ...
Dec 17, 2018
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British researchers have identified specific resistance mutations for two classes of p7 inhibitor, which may explain their lack of effectiveness in clinical trials combined with current standard of care. Study results support ...
Jun 28, 2011
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In epilepsy, nerve cells lose their usual rhythm, and ion channels, which have a decisive influence on their excitability, are involved. A team of researchers under the direction of the University of Bonn has now discovered ...
Nov 19, 2015
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Researchers in Rhode Island Hospital's Cardiovascular Research Center have published two new studies focusing on the causes of arrhythmia and sudden cardiac death (SCD) when a genetic disorder is present. The studies use ...
Jan 17, 2012
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Imagine two flat screen televisions tuned to the same channel and sitting side-by-side. From a distance, their pictures are virtually the same, however up close, you can see subtle variations in the pixels – one blurred ...
Jun 23, 2011
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