News tagged with journal of clinical investigation
New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune respon ...
Cancer Mar 01, 2013 | 5 / 5 (2) | 0 |
Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD)—a form of early-onset dementia that is similar to Alzheimer's disease. ...
Neuroscience Oct 08, 2012 | not rated yet | 0 |
How does one's experience of an event get translated into a memory that can be accessed months, even years later? A team led by University of Pennsylvania scientists has come closer to answering that question, identifying ...
Medical research Sep 10, 2012 | 5 / 5 (6) | 3 |
Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy.
Cancer Jul 02, 2012 | 5 / 5 (3) | 0 |
A novel mechanism for anxiety behaviors, including a previously unrecognized inhibitory brain signal, may inspire new strategies for treating psychiatric disorders, University of Chicago researchers report.
Genetics May 15, 2012 | 4.5 / 5 (4) | 0 |
Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis (TB), they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meanin ...
Diseases, Conditions, Syndromes Apr 25, 2011 | 5 / 5 (1) | 0 |
Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in ...
Medical research May 15, 2013 | 4.8 / 5 (4) | 0 |
Researchers discovered that small pieces of genetic material called microRNAs link the two defining characteristics of fit muscles: the ability to burn sugar and fat and the ability to switch between slow- ...
Medical research May 08, 2013 | 5 / 5 (2) | 0 |
A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN. The finding ...
Medical research Apr 29, 2013 | 5 / 5 (1) | 1 |
Stanford University School of Medicine scientists have created a mouse model of muscular dystrophy in which degenerating muscle tissue gives off visible light. The observed luminescence occurs only in damaged muscle tissue ...
Medical research Apr 24, 2013 | 5 / 5 (3) | 0 |
Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.
Cancer Apr 16, 2013 | not rated yet | 0 |
(Medical Xpress)—A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be ...
Genetics Apr 05, 2013 | 4.5 / 5 (2) | 0 |
A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral ...
Medical research Apr 01, 2013 | not rated yet | 0 |
Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.
Medical research Mar 25, 2013 | 4.5 / 5 (2) | 0 |
Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Medical research Mar 01, 2013 | 5 / 5 (2) | 0 |
Journal of Clinical Investigation
The Journal of Clinical Investigation (JCI or J Clin Invest) is a leading biomedical journal, with a 2008 impact factor of 16.559. The journal makes its research articles -- including access to articles back to 1924 -- freely available online.
The website of the journal describes it as "a premier venue for critical advances in biomedical research, authoritative reviews, and commentaries that place research articles in context." The first issue of the journal appeared in 1924, and within a few decades, it had established itself as a reputed journal for primary clinical research.
The JCI's Editorial Board is unique in that its members are located chiefly at a singular academic medical center and are predominantly members of the American Society for Clinical Investigation. The leadership of the Editorial Board changes every five years: As of March 2007, the Editorial Board is located at the University of Pennsylvania under the leadership of Laurence A. Turka, M.D. From March 2002 to March 2007, the Editorial Board was located at Columbia University under the leadership of Andrew Marks, M.D. Ushma S. Neill, formerly with Nature Medicine, is the journal's Executive Editor.
This monthly journal publishes original research and review articles, including periodic review series focusing on important topics in biomedicine.
For more information about Journal of Clinical Investigation, read the full article at
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