Lung cancer mortality rates linked to primary care provider density
Lung cancer remains the leading cause of cancer-related deaths and is tied as the third leading cause of death overall in industrialized countries. Within the United States, several groups identified by race, sex, and socioeconomic ...
Cancer
Apr 22, 2013 |
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Latest research shows two items are key to decrease symptoms and prolong survival for LMC patients
Lung cancer is one of the most common primary cancers that cause leptomeningeal carcinomatosis (LMC), when cancer spreads to the membranes surrounding the spinal cord and brain. Cases of LMC have increased because of the ...
Cancer
Apr 22, 2013 |
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Many doctors do not provide tobacco cessation assistance to lung cancer patients
Physicians who care for lung cancer patients recognize the importance of tobacco cessation, but often do not provide cessation assistance to their patients according to a recent study published in the Journal of Thoracic On ...
Cancer
Mar 28, 2013 |
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Pathologists identify patterns of mutations to help inform design of future trials
Molecular driven therapeutic targets have resulted in a paradigm shift in the treatment of advanced lung adenocarcinoma. However, in early non-small cell lung cancer (NSCLC), surgical resection remains the treatment of choice ...
Cancer
Mar 22, 2013 |
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Greater representation of elderly patients in Phase III trials are needed
The median age of patients diagnosed with advanced non–small-cell lung cancer (NSCLC) has steadily increased over the recent years and is presently 70 years. Despite this, the elderly are significantly underrepresented ...
Cancer
Feb 22, 2013 |
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Local therapy followed by treatment with EGFR TKI is well tolerated
Local therapy is not commonly utilized in metastatic lung cancer. Researchers at Memorial Sloan-Kettering Cancer Center investigated the efficacy of local therapy with continued EGFR TKI therapy specifically in patients with ...
Cancer
Feb 22, 2013 |
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Comparable patterns of failure between SBRT, lobectomy or pneumonectomy for stage I NSCLC
For patients with medically operable clinical stage I non–small-cell lung cancer (NSCLC), lobectomy or pneumonectomy is the standard approach. For patients with medically inoperable stage I NSCLC, stereotactic body radiotherapy ...
Cancer
Jan 15, 2013 |
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EGFR mutation not prognostic factor in non-small cell lung cancer
Recent studies have demonstrated that molecular-targeted agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), may prolong survival of selected patients based on tumor biomarkers. The presence ...
Cancer
Jan 15, 2013 |
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Patients with EGFR exon 20 insertions have poorer prognosis
Exon 20 insertions are the third most common family of epidermal growth factor receptor (EGFR) mutations found in non–small-cell lung cancer (NSCLC). Little is known about cancers harboring these mutations aside from their ...
Cancer
Jan 15, 2013 |
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Study shows COPD is not independent risk factor for lung cancer
Chronic obstructive pulmonary disease (COPD) and lung cancer are two of the most important smoking-related diseases worldwide, with a huge combined mortality bur¬den. Many consider the presence of COPD itself to be an independent ...
Cancer
Dec 15, 2012 |
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Study shows immunohistochemistry is reliable screening tool for ALK rearrangement
Favorable results have led to crizotinib gaining approval for the treatment of advanced stage ALK-positive non-small cell lung cancer (NSCLC) in Japan, the United States, Canada, and several other countries in Europe and ...
Cancer
Dec 15, 2012 |
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Study confirms prognostic value of new IASLC/ATS/ERS adenocarcinoma sub-classification
The International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS), and the European Respiratory Society (ERS), have proposed a new sub-classification of lung adenocarcinomas. A growing ...
Cancer
Dec 15, 2012 |
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Lung cancer patients with pockets of resistance prolong disease control by 'weeding the garden'
The central skill of cancer is its ability to mutate – that's how it became cancerous in the first place. Once it's started down that path, it's not so difficult for a cancer cell to mutate again and again. This means that ...
Cancer
Dec 01, 2012 |
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Study shows bone metastases treatment can improve overall survival
It is common for patients initially diagnosed with lung cancer to have the cancer spread to sites like the liver, brain and bone. One of the most frequent sites of metastases is the bone, with an estimated 30 to 40 percent ...
Cancer
Nov 15, 2012 |
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Study shows different approach after progression in non-small cell lung cancer patients
Right now, the best known treatment for patients with metastatic non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase gene rearrangements (ALK) or epidermal growth factor receptor mutations (EGFR) is crizotinib ...
Cancer
Nov 15, 2012 |
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