HIV & AIDS
How an approach called 'shock and kill' could cure HIV
Current HIV medications can effectively prevent the disease's progression, but the virus can lurk for a lifetime in the body.
Dec 1, 2015
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News tagged with latent infection
Diseases, Conditions, Syndromes
Study sheds light on why parasite makes TB infections worse
Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are ...
Nov 16, 2015
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HIV & AIDS
Kicking latent HIV: New strategies to reactivate reservoirs of latent infection
In cells with latent HIV infection, the virus is dormant, and such cells are therefore not attacked by the immune system or by standard antiretroviral therapy. To eradicate the virus from the human body and truly cure a patient, ...
Jul 30, 2015
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HIV & AIDS
Waking up HIV: Two compounds show great potential to rouse latent virus
Highly active anti-retroviral therapy (HAART) has helped millions survive the human immunodeficiency virus (HIV). Unfortunately, HIV has a built-in survival mechanism, creating reservoirs of latent, inactive virus that are ...
Jul 30, 2015
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HIV & AIDS
New model to study HIV latency in brain cells
Over 35 million people worldwide are currently infected by HIV. Antiviral therapies can keep the virus from multiplying. However, no drug can cure infection so far, because various cell types continue to carry the virus in ...
Jun 18, 2015
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Immunology
How the human immune system keeps tuberculosis at bay
A new tissue culture model using human white blood cells shows how people with a latent - or symptom-free - tuberculosis infection are protected from active disease by a critical early step in their immune response, researchers ...
Mar 26, 2015
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Diseases, Conditions, Syndromes
Scientists use DNA sequencing to trace the spread of drug-resistant TB
Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK.
Mar 23, 2015
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Genetics
Genetic discovery provides clues to how TB may evade the immune system
The largest genetic study of tuberculosis (TB) susceptibility to date has led to a potentially important new insight into how the pathogen manages to evade the immune system. Published today in the journal Nature Genetics, ...
Mar 16, 2015
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Pediatrics
Shorter Combination treatment as effective as monotherapy for TB prevention in kids
To prevent tuberculosis (TB) in children with latent tuberculosis infection (which is not active but can become active), combination treatment with the medications rifapentine and isoniazid was as effective as longer treatment ...
Jan 12, 2015
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Diseases, Conditions, Syndromes
New whole blood assay may help overcome roadblocks to TB eradication
One of the roadblocks to the eradication of tuberculosis (TB) is the difficulty in identifying patients with latent TB infections (LTBI). Neither the tuberculin skin test (TST) nor interferon-gamma release assays (IGRAs) ...
Jan 6, 2015
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