News tagged with lipitor

Related topics: drug , pfizer , cholesterol

Should everyone over 65 take a statin?

(HealthDay)—Men and women over 65 who are at risk for cardiovascular disease but don't have any known heart problems might benefit from cholesterol-lowering drugs, a new study suggests.

Aug 28, 2013
popularity 3.5 / 5 (4) | comments 0 | with audio podcast

Pfizer Q1 profit up, but drugmaker cuts outlook

Pfizer Inc.'s first-quarter net income rose 53 percent despite falling sales, mainly because the world's second-largest drugmaker took big charges a year ago. Pfizer's results fell short of Wall Street's ...

Apr 30, 2013
popularity not rated yet | comments 0

Pfizer Q4 net jumps on sale of nutrition business

Pfizer Inc.'s fourth-quarter profit more than quadrupled, despite competition from generic drugs hurting sales of Lipitor and other medicines, because of a $4.8 billion gain from selling its nutrition business. ...

Jan 29, 2013
popularity not rated yet | comments 0

Drugmaker Ranbaxy halts generic Lipitor production

Problem-plagued Ranbaxy Pharmaceuticals Inc. has halted production of generic cholesterol drug Lipitor while it investigates how tiny glass particles got into the ingredients used for dozens of batches of the drug that were ...

Nov 30, 2012
popularity not rated yet | comments 0

Ranbaxy recalls generic Lipitor doses

(AP)—Ranbaxy Pharmaceuticals Inc. has recalled dozens of lots of its generic version of cholesterol drug Lipitor because some may contain tiny glass particles, the latest in a string of manufacturing deficiencies that once ...

Nov 23, 2012
popularity not rated yet | comments 0

Pfizer 3Q profit falls 14 pct on generic Lipitor (Update)

(AP)—Drug giant Pfizer Inc. said Thursday that its third-quarter profit fell 14 percent as sales plunged, mainly due to U.S. generic competition to cholesterol fighter Lipitor, long the world's top-selling drug.

Nov 01, 2012
popularity not rated yet | comments 0

Pfizer 2Q net income rises 25 pct on lower costs

Drugmaker Pfizer Inc.'s second-quarter net income jumped 25 percent as sharply lower costs for production, marketing and restructuring more than offset a plunge in revenue from cholesterol fighter Lipitor ...

Jul 31, 2012
popularity not rated yet | comments 0

Counterfeit drugs becoming big business worldwide

(AP) -- The discovery that a fake version of the widely used cancer medicine Avastin is circulating in the United States is raising new fears that the multibillion-dollar drug-counterfeiting trade is increasingly ...

Feb 16, 2012
popularity 5 / 5 (1) | comments 1

Atorvastatin

Atorvastatin (INN) ( /əˌtɔrvəˈstætən/), sold by Pfizer under the trade name Lipitor, is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.

Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Parke-Davis Warner-Lambert Company (now Pfizer). With 2008 sales of US$12.4 billion, Lipitor was the top-selling branded pharmaceutical in the world. U.S. patent protection was scheduled to expire in June 2011. However, Pfizer made an agreement with Ranbaxy Laboratories to delay the generic launch in the U.S. until November 30, 2011.

This text uses material from Wikipedia licensed under CC BY-SA