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Lithium

Lithium (pronounced /ˈlɪθiəm/) is the chemical element with atomic number 3, and is represented by the symbol Li. It is a soft alkali metal with a silver-white color. Under standard conditions it is the lightest metal and the least dense solid element. Like all alkali metals lithium is highly reactive, corroding quickly in moist air to form a black tarnish. For this reason lithium metal is typically stored under the cover of oil. When cut open lithium exhibits a metallic luster, but contact with oxygen quickly turns it back to a dull silvery gray color. Lithium in its elemental state is highly flammable.

According to theory, lithium was one of the few elements synthesized in the Big Bang. Since its current estimated abundance in the universe is vastly less than that predicted by theory; the processes by which new lithium is created and destroyed, and the true value of its abundance, continue to be active matters of study in astronomy. The nuclei of lithium are relatively fragile: the two stable lithium isotopes found in nature have lower binding energies per nucleon than any other stable compound nuclides, save for the exotic and rare deuterium, and 3He. Though very light in atomic weight, lithium is less common in the solar system than 25 of the first 32 chemical elements.

Due to its high reactivity it only appears naturally in the form of compounds. Lithium occurs in a number of pegmatitic minerals, but is also commonly obtained from brines and clays. On a commercial scale, lithium metal is isolated electrolytically from a mixture of lithium chloride and potassium chloride.

Trace amounts of lithium are present in the oceans and in some organisms, though the element serves no apparent vital biological function in humans. However, the lithium ion Li+ administered as any of several lithium salts has proved to be useful as a mood stabilizing drug due to neurological effects of the ion in the human body. Lithium and its compounds have several industrial applications, including heat-resistant glass and ceramics, high strength-to-weight alloys used in aircraft, and lithium batteries. Lithium also has important links to nuclear physics. The transmutation of lithium atoms to tritium was the first man-made form of a nuclear fusion reaction, and lithium deuteride serves as a fusion fuel in staged thermonuclear weapons.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.


New drug for bipolar disorder may offer fewer side effects

(Medical Xpress)—A drug for bipolar disorder that works like lithium, the most common and effective treatment for the condition, but without lithium's toxicity and problem side-effects has been identified ...

Psychology & Psychiatry created Jan 09, 2013 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Body clocks may hold key for treatment of bipolar disorder

Scientists have gained insight into why lithium salts are effective at treating bipolar disorder in what could lead to more targeted therapies with fewer side-effects.

Psychology & Psychiatry created Mar 13, 2012 | popularity 4.3 / 5 (6) | comments 1 | with audio podcast

Lithium shows no benefit to MND patients

(Medical Xpress)—Results from a clinical trial into amyotrophic lateral sclerosis (ALS), led by King's College London's Institute of Psychiatry show that lithium carbonate is ineffective at treating the ...

Neuroscience created Mar 19, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Giving lithium to those who need it

Lithium is a 'gold standard' drug for treating bipolar disorder, however not everyone responds in the same way. New research published in BioMed Central's open access journal Biology of Mood & Anxiety Disorders finds that t ...

Psychology & Psychiatry created Sep 21, 2012 | popularity 4 / 5 (1) | comments 0

Psychiatric medication effects on brain structure

It is increasingly recognized that chronic psychotropic drug treatment may lead to structural remodeling of the brain. Indeed, clinical studies in humans present an intriguing picture: antipsychotics, used for the treatment ...

Psychology & Psychiatry created May 08, 2012 | popularity not rated yet | comments 0 | with audio podcast

Lithium profoundly prevents brain damage associated with Parkinson's disease

Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.

Parkinson's & Movement disorders created Jun 24, 2011 | popularity 5 / 5 (2) | comments 0

Lithium treatment can cause weight-gain, hypothyroidism, and hyperparathoidism

Lithium is the most effective long-term therapy for bipolar disorder, protecting against both depression and mania and reducing the risk of suicide and short-term mortality. However, safety concerns have made its use controversial.

Psychology & Psychiatry created Jan 19, 2012 | popularity not rated yet | comments 0

The hunt for a successor to lithium for bipolar disorder

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body—with an eye ...

Psychology & Psychiatry created Mar 27, 2013 | popularity not rated yet | comments 0

Lithium restores cognitive function in Down syndrome mice

Down syndrome is a neurodevelopmental disorder that is the leading cause of genetically defined intellectual disability. In the brain, Down syndrome results in alterations in the connections between neurons and a reduction ...

Neuroscience created Dec 03, 2012 | popularity 5 / 5 (3) | comments 1

Researchers reveal formula for success in increasing smoke alarm use

(PhysOrg.com) -- The most effective strategy to encourage more people to have a working smoke alarm in their homes has been revealed by a team of healthcare researchers.

Health created Dec 16, 2011 | popularity not rated yet | comments 0