Metabolic (bariatric) surgery is more effective than medications and lifestyle interventions for the treatment of advanced non-alcoholic fatty liver disease.
Apr 20, 2023
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113
In research published in The FASEB Journal, scientists have discovered that a molecule called Yes-associated protein (YAP) plays a key role in the development of liver scarring, or fibrosis, by influencing the behavior of ...
Apr 19, 2023
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Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease. Named Lyn kinase-associated vasculopathy and liver fibrosis (LAVLI), ...
Mar 28, 2023
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Three-dimensional MR elastography (MRE) scans have demonstrated the potential to assess both liver fibrosis and inflammation simultaneously. However, researchers face challenges in that current 3D MRE approaches typically ...
Mar 16, 2023
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Barely a month goes by without headlines announcing yet another advancement in cancer vaccines.
Mar 7, 2023
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A new study by the University of Coimbra, published in Nutrients, has revealed that caffeine, polyphenols, and other natural products found in coffee may help reduce the severity of non-alcoholic fatty liver disease (NAFLD) ...
Jan 12, 2023
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About 10 percent of patients with psoriasis have a high risk for advanced liver fibrosis, according to a systematic review and meta-analysis published online Dec. 15 in Frontiers in Medicine.
Jan 4, 2023
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Using the latest technologies—including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells—researchers have uncovered novel ...
Jan 4, 2023
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Investigators from the Smidt Heart Institute at Cedars-Sinai have found that even subtle forms of liver disease directly impact heart health. The findings, recently published in the journal Frontiers in Cardiovascular Medicine, ...
Dec 8, 2022
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A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes, including YAP, CTGF, TGF-β, and ...
Nov 8, 2022
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