Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targeting a different type of immune cell called macrophages could be a more effective approach, ...
Mar 16, 2023
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Scientists have long known that mitochondria play a crucial role in the metabolism and energy production of cancer cells. However, until now, little was known about the relationship between the structural organization of ...
Mar 15, 2023
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Immune checkpoint inhibitors that activate T cells to target cancer cells have greatly improved patient outcomes across a variety of tumor types. But not all patients respond to the therapies. Moffitt Cancer Center researchers ...
Feb 13, 2023
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A new study validating the clinical utility of a proprietary pan-solid tumor predictive biomarker for anti-PD-1/PD-L1 checkpoint inhibitor monotherapy benefit—called Immunotherapy Response Score (IRS)—was published in ...
Feb 7, 2023
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A study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Cell Biology, details a previously unexplained type of cell death called disulfidptosis that could open the door for ...
Feb 6, 2023
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Primary lung neuroendocrine tumors are very rare tumors that represent about 1-2% of all lung cancer cases. Only 2,000 to 4,500 are diagnosed in the U.S. each year. The common treatment for early stage lung neuroendocrine ...
Feb 3, 2023
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Immunotherapy—drug treatment that stimulates the immune system to attack tumors—works well against some types of cancer, but it has shown mixed success against lung cancer.
Feb 2, 2023
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Lung cancer claims more lives each year than any other type of cancer worldwide. According to the World Health Organization, an estimated 1.8 million people died of lung cancer in 2020. Current treatments rely on one of two ...
Feb 1, 2023
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Sometimes research takes scientists to unexpected places, even alpaca farms. Tobiloba Oni is one of two Valhalla Fellows at Whitehead Institute who are researching ways to harness our natural defenses to combat cancer, an ...
Jan 18, 2023
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Northwestern Medicine investigators have revealed new insights into how cancer cells can change their form by undergoing phenotypic "switches" to facilitate tumor growth and treatment resistance in small cell lung cancer, ...
Jan 11, 2023
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