Neuroscience

Motor neuron toxin associated with ALS identified

An international team of investigators has discovered that an inorganic polyphosphate released by nerve cells known as astrocytes in people with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) contributes ...

Genetics

Arrhythmia genes more common than previously thought

By sequencing known genes associated with cardiac arrhythmia risk in more than 20,000 people without an indication for genetic testing, scientists were able to identify pathogenic and likely pathogenic variants in nearly ...

Genetics

Redefining human diseases through the lens of DNA

Throughout most of medical history, physicians have diagnosed individuals with various diseases based upon their description and presentation of clinical symptoms. In recent years, investigations using genome-wide association ...

Genetics

Genomic autopsy identifies cardiomyopathy variants

Postmortem genetic testing, or genomic autopsy, of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy, according to a Northwestern Medicine study ...

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