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News tagged with melatonin

Dark matter DNA active in brain during day-night cycle

(Medical Xpress)—Long stretches of DNA once considered inert dark matter appear to be uniquely active in a part of the brain known to control the body's 24-hour cycle, according to researchers at the National Institutes ...

Medical research created Sep 24, 2012 | popularity 3 / 5 (2) | comments 2 | with audio podcast

Decreased melatonin secretion associated with higher risk of developing type 2 diabetes

With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased risk for the development ...

Diabetes created Apr 02, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study finds homeschool students sleep better: Research supports later start times for high school

(Medical Xpress)—In the first study of its kind, researchers have determined that teens who are homeschooled benefit from healthier sleep habits than those who go to most private and public schools. The findings provide ...

Health created Mar 07, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Light from self-luminous tablet computers can affect evening melatonin, delaying sleep

(Medical Xpress)—A new study from the Lighting Research Center (LRC) at Rensselaer Polytechnic Institute shows that a two-hour exposure to electronic devices with self-luminous "backlit" displays causes ...

Medical research created Aug 27, 2012 | popularity 3.7 / 5 (6) | comments 2 | with audio podcast

Night shift might boost women's breast cancer risk: study

(HealthDay) -- Women who work the night shift more than twice a week might be increasing their risk for breast cancer, Danish researchers find.

Health created May 29, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study raises questions about use of anti-epilepsy drugs in newborns

A brain study in infant rats demonstrates that the anti-epilepsy drug phenobarbital stunts neuronal growth, which could prompt new questions about using the first-line drug to treat epilepsy in human newborns.

Neuroscience created May 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Genetic study links body clock receptor to diabetes

A study published in Nature Genetics today has found new evidence for a link between the body clock hormone melatonin and type 2 diabetes. The study found that people who carry rare genetic mutations in the receptor for me ...

Diabetes created Jan 29, 2012 | popularity 4 / 5 (2) | comments 0 | with audio podcast

Tireless research reveals secrets of the 'sleep hormone'

A team from the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University has made a major breakthrough by unraveling the inner workings of melatonin, also known as the "sleep hormone." The ...

Neuroscience created Dec 13, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Melatonin delays onset, reduces deaths in mouse model of Huntington's disease

Melatonin, best known for its role in sleep regulation, delayed the onset of symptoms and reduced mortality in a mouse model of Huntington's disease, say researchers at the University of Pittsburgh School of Medicine and ...

Neuroscience created Oct 11, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Modern shift work pattern potentially less harmful to health

Recent research suggests that the modern day-day-night-night shift pattern for shift workers may not be as disruptive or as potentially carcinogenic as older, more extreme shift patterns.

Health created Sep 27, 2011 | popularity not rated yet | comments 0 | with audio podcast

'White' light suppresses the body's production of melatonin

Exposure to the light of white LED bulbs, it turns out, suppresses melatonin 5 times more than exposure to the light of High Pressure Sodium bulbs that give off an orange-yellow light. "Just as there are regulations and standards ...

Health created Sep 12, 2011 | popularity 5 / 5 (19) | comments 23 | with audio podcast

Aging eyes linked to sleepless nights, new study shows

A natural yellowing of the eye lens that absorbs blue light has been linked to sleep disorders in a group of test volunteers, according to a study in the September 1 issue of the journal Sleep. As this type of lens discol ...

Health created Sep 01, 2011 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Team finds melatonin delays ALS symptom onset and death in mice

Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new study by researchers at ...

Neuroscience created Apr 25, 2013 | popularity not rated yet | comments 0

Oral melatonin has no effect on appetite in advanced cancer

(HealthDay)—Oral melatonin does not improve appetite, weight, or quality of life for patients with cachexia due to advanced cancer, according to research published online Feb. 25 in the Journal of Clinical On ...

Cancer created Mar 16, 2013 | popularity not rated yet | comments 0

Scientists develop a pioneering technique to effectively treat mucositis

Investigators at the University of Granada have patented a melatonin gel that is 100% effective against this inflammatory reaction.

Cancer created Feb 14, 2013 | popularity not rated yet | comments 0

Melatonin

Melatonin i/ˌmɛləˈtoʊnɪn/, also known chemically as N-acetyl-5-methoxytryptamine, is a naturally occurring compound found in animals, plants, and microbes. In animals, circulating levels of the hormone melatonin vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions.

Many biological effects of melatonin are produced through activation of melatonin receptors, while others are due to its role as a pervasive and powerful antioxidant, with a particular role in the protection of nuclear and mitochondrial DNA.

In mammals, melatonin is secreted into the blood by the pineal gland in the brain. Known as the "hormone of darkness," it is secreted in darkness in both day-active (diurnal) and night-active (nocturnal) animals.

It may also be produced by a variety of peripheral cells such as bone marrow cells, lymphocytes, and epithelial cells. Usually, the melatonin concentration in these cells is much higher than that found in the blood, but it does not seem to be regulated by the photoperiod.

Research has shown that when bird chicks ingest melatonin-rich plant feed, such as rice, the melatonin binds to melatonin receptors in their brains. No food has been found to elevate plasma melatonin levels in humans.

Products containing melatonin have been available over-the-counter as dietary supplements in the United States since the mid-1990s. In many other countries, the over-the-counter sale of this neurohormone is not permitted or requires a prescription, and the U.S. Postal Service lists unapproved melatonin preparations among items prohibited by Germany.

For more information about Melatonin, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: sleep