News tagged with metabolic stress

Hijacking stress response in cancer

(Medical Xpress)—Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress ...

Jul 02, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

New factor to control oncogene-induced senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induce ...

May 21, 2013
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Losing sleep? Scientists evaluate why

The issue of sleep deprivation has gone beyond the counting of sheep and into the scientific domain, as European researchers set up 'sleep labs' to study the biomedical and sociological factors keeping us ...

May 03, 2013
popularity 5 / 5 (3) | comments 0

Discovery spurred by unique twist of fate

(Medical Xpress)—As people age, or as a result of poor nutrition, heart valves can become damaged by the accumulation of calcium deposits within the tissue. This calcification causes a thickening and hardening ...

Feb 21, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast