News tagged with metabolic stress


New factor to control oncogene-induced senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induce ...

Cancer created May 21, 2013 | popularity not rated yet | comments 0

Posttraumatic stress disorder associated with type 2 diabetes

The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gießen ...

Psychology & Psychiatry created May 16, 2013 | popularity 5 / 5 (1) | comments 0

Losing sleep? Scientists evaluate why

The issue of sleep deprivation has gone beyond the counting of sheep and into the scientific domain, as European researchers set up 'sleep labs' to study the biomedical and sociological factors keeping us ...

Health created May 03, 2013 | popularity 5 / 5 (3) | comments 0

Researchers find that alcohol consumption damages brain's support cells

Alcohol consumption affects the brain in multiple ways, ranging from acute changes in behavior to permanent molecular and functional alterations. The general consensus is that in the brain, alcohol targets mainly neurons. ...

Neuroscience created Mar 18, 2013 | popularity 3 / 5 (1) | comments 0

Discovery spurred by unique twist of fate

(Medical Xpress)—As people age, or as a result of poor nutrition, heart valves can become damaged by the accumulation of calcium deposits within the tissue. This calcification causes a thickening and hardening ...

Cardiology created Feb 21, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Stem cell survival strategy key to blood and immune system health

Stem cells of the aging bone marrow recycle their own molecules to survive and keep replenishing the blood and immune systems as the body ages, researchers at UC San Francisco (UCSF) have discovered.

Medical research created Feb 14, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Diabetes drug could hold promise for lung cancer patients

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...

Cancer created Jan 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Cancer created Jan 13, 2013 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Researchers identify new target for common heart condition

Researchers have found new evidence that metabolic stress can increase the onset of atrial arrhythmias, such as atrial fibrillation (AF), a common heart condition that causes an irregular and often abnormally fast heart rate. ...

Cardiology created Jan 08, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Liver mitochondria improve, increase after chronic alcohol feeding in mice

(Medical Xpress)—Scientists at the Keck School of Medicine of the University of Southern California (USC) have found evidence that liver mitochondria in mice adapt to become better metabolizers of alcohol and increase in ...

Medical research created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists identify molecular process in fat cells that influences stress and longevity

As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor—microRNA ...

Medical research created Sep 26, 2012 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Lack of sleep affects bone health and bone marrow activity

Scientists at the Medical College of Wisconsin, in a team led by Carol Everson, Ph.D., professor of neurology, cell biology, neurobiology and anatomy, have discovered abnormalities in bone and bone marrow in rats undergoing ...

Medical research created Sep 18, 2012 | popularity 5 / 5 (2) | comments 0

Treatment target for diabetes, Wolfram syndrome

Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that ...

Inflammatory disorders created Aug 07, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Stress during pregnancy leads to abdominal obesity in mice offspring

A new report involving mice suggests that a relationship exists between maternal metabolic or psychological stress and the development of obesity, type 2 diabetes, and metabolic syndrome in her offspring. What's more, the ...

Obstetrics & gynaecology created Jul 31, 2012 | popularity not rated yet | comments 0 | with audio podcast

Genetic variant is linked to obesity and insulin resistance

A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented ...

Genetics created Jun 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast