Research team breakthrough in delivering drugs to the brain
Researchers at UCL have made a breakthrough in the way that drugs could be delivered to the brain.
Medical research
Mar 11, 2013 |
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Accelerating drug development
All human clinical trials of new treatments begin with phase I, where drugs are tested in isolation to confirm their safety. Yet most effective cancer treatments use a combination of drugs, so-called 'multi-agent' ...
Medications
Mar 08, 2013 |
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Secrets of a t-haplotype gene revealed: Decade-long hunt turns up key gene involved in early mammalian development
The t haplotype in mice—a block of linked genes occupying the proximal half of mouse chromosome 17—is one of the best-studied examples of a selfish genetic element. Through an elaborate sperm-poisoning ...
Genetics
Mar 08, 2013 |
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Using human brain cells to make mice smarter
Glial cells – a family of cells found in the human central nervous system and, until recently, considered mere "housekeepers" – now appear to be essential to the unique complexity of the human brain. Scientists reached ...
Medical research
Mar 07, 2013 |
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Drugs targeting blood vessels may be candidates for treating Alzheimer's
(Medical Xpress)—University of British Columbia researchers have successfully normalized the production of blood vessels in the brain of mice with Alzheimer's disease (AD) by immunizing them with amyloid beta, a protein ...
Alzheimer's disease & dementia
Mar 07, 2013 |
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Flip of a single molecular switch makes an old brain young
The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine ...
Neuroscience
Mar 06, 2013 |
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Visceral fat causally linked to intestinal cancer
Visceral fat, or fat stored deep in the abdominal cavity, is directly linked to an increased risk for colon cancer, according to data from a mouse study published in Cancer Prevention Research, a journal of the American Associ ...
Cancer
Mar 06, 2013 |
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Obesity makes fat cells act like they're infected
(Medical Xpress)—The inflammation of fat tissue is part of a spiraling series of events that leads to the development of type 2 diabetes in some obese people. But researchers have not understood what triggers ...
Medical research
Mar 05, 2013 |
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Novel storage mechanism allows command, control of memory
(Medical Xpress)—Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your ...
Neuroscience
Mar 05, 2013 |
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Researchers discover gene that causes obesity in mice
Researchers have discovered that deleting a specific gene in mice prevents them from becoming obese even on a high fat diet, a finding they believe may be replicated in humans.
Medical research
Mar 05, 2013 |
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Mammalian placenta reflects exposure to stress, impacts offsprings' brains, research finds
The mammalian placenta is more than just a filter through which nutrition and oxygen are passed from a mother to her unborn child. According to a new study by a research group from the University of Pennsylvania School of ...
Medical research
Mar 04, 2013 |
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Losing weight sooner has best chance to reverse heart damage, mouse study shows
Johns Hopkins research on obese mice finds that the impact of dieting and losing weight benefits the heart health of the young, but not the older ones
Cardiology
Mar 04, 2013 |
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Combination of stresses may produce brain disorders, research shows
(Medical Xpress)—A new study in a mouse model has shown that neuropsychiatric disorders in adults were more likely to develop if the mice had suffered immune challenges before birth and stresses after birth. ...
Medical research
Mar 01, 2013 |
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New model could lead to improved treatment for early stage Alzheimer's
Researchers at the University of Florida and The Johns Hopkins University have developed a line of genetically altered mice that model the earliest stages of Alzheimer's disease. This model may help scientists identify new ...
Alzheimer's disease & dementia
Feb 28, 2013 |
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Progesterone may be why pregnant women are more vulnerable to certain infections
Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus. A new research report appearing ...
Medical research
Feb 28, 2013 |
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