The top contributor to familial Parkinson's disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies. University of California, ...
Feb 18, 2020
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How do nerve cells—which can each be up to three feet long in humans—keep from rupturing or falling apart?
Apr 15, 2013
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Sometimes in science, "Eureka!" moments happen with surprisingly little effort. Sometimes they take years or decades to emerge. Such was the case with Brian Kraemer's research team and their recent study of the protein tau ...
Feb 6, 2023
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Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences.
Nov 2, 2021
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The failure of pancreatic beta cells to release appropriate amounts of insulin in response to rising blood glucose levels is a hallmark of type 2 diabetes.
Aug 1, 2019
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While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, ...
Jul 19, 2012
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Compared to the monumental machines of science, things like the International Space Station or the Large Hadron Collider, the human brain doesn't look like much. However, this three-pound amalgam of squishy cells is one of ...
May 6, 2014
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A Northwestern Medicine study found the human immunodeficiency virus (HIV) uses proteins called diaphanous-related formins (DRFs) to hijack the cytoskeleton of healthy cells, findings that deepen the understanding of HIV ...
Sep 27, 2017
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As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.
Oct 2, 2012
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A new molecule with anti-cancer and anti-metastatic properties has been discovered by teams from CNRS, CEA, the Institut Curie and Inserm, in collaboration with Australian and British researchers. This anticancer drug acts ...
Sep 4, 2012
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