Oncology & Cancer

Protein predicts breast cancer prognosis

Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating therapies, while insuring ...

Medical research

Newly found protein helps cells build tissues

As they work together to form body parts, cells in developing organisms communicate like workers at a construction site. The discovery of a new signaling molecule in flies by Brown University biologists not only helps explain ...

Oncology & Cancer

COUP-TFII sparks prostate cancer progression

Prostate cancer presents a dilemma for patients and the physicians who treat them. Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and which need aggressive ...

Oncology & Cancer

Loss of tumor suppressor SPOP releases cancer potential of SRC-3

Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers ...

Oncology & Cancer

Diabetes drug could hold promise for lung cancer patients

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work ...

Oncology & Cancer

'Big data' technology shows promise in breast cancer research

Only eight months into its $100 million, five-year enterprise analytics effort, UPMC and its research partners at the University of Pittsburgh are starting to see the potential of this "big data" technology for accelerating ...

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