News tagged with monoclonal antibodies

Monoclonal antibody appears effective and safe in asthma Phase IIa trial

A novel approach to obstructing the runaway inflammatory response implicated in some types of asthma has shown promise in a Phase IIa clinical trial, according to U. S. researchers.

Diseases, Conditions, Syndromes created 3 hours ago | popularity not rated yet | comments 0

Palivizumab cuts number of days of wheezing in preemies

(HealthDay)—Many pre-term babies suffer recurrent episodes of wheezing. Now, researchers say a common infection is a likely culprit and they may be able to prevent the breathing problems.

Diseases, Conditions, Syndromes created May 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

Cancer created Apr 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Monoclonal antibody targets, kills leukemia cells

Researchers at the University of California, San Diego Moores Cancer Center have identified a humanized monoclonal antibody that targets and directly kills chronic lymphocytic leukemia (CLL) cells.

Cancer created Mar 25, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Monthly shot lowers cholesterol 66 percent: study

A monthly injection of an experimental drug made by the US biotech firm Amgen reduced patients' cholesterol by up to 66 percent, according to a small study described at a US cardiology conference.

Cardiology created Mar 26, 2012 | popularity 5 / 5 (2) | comments 5

Statin alternative looks promising in early trials

(HealthDay) -- Administration of REGN727, a monoclonal antibody to proprotein convertase subtilisin/kexin 9 (PCSK9), significantly reduces low-density lipoprotein (LDL) cholesterol levels, according to the ...

Cardiology created Mar 22, 2012 | popularity 3 / 5 (1) | comments 1 | with audio podcast

Ebola antibody treatment, produced in plants, protects monkeys from lethal disease

A new Ebola virus study resulting from a widespread scientific collaboration has shown promising preliminary results, preventing disease in infected nonhuman primates using monoclonal antibodies.

Medical research created Oct 15, 2012 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Dual action polyclonal antibody may offer more effective, safer protection against osteoporosis

A new study suggests that a polyclonal antibody that blocks follicle-stimulating hormone (FSH) in mice without ovaries might offer a more effective way to prevent or arrest osteoporosis than currently available treatments.

Medical research created Aug 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers develop novel anti-body vaccine that blocks addictive nicotine chemicals from reaching the brain

Researchers at Weill Cornell Medical College have developed and successfully tested in mice an innovative vaccine to treat nicotine addiction.

Medical research created Jun 27, 2012 | popularity 5 / 5 (7) | comments 7 | with audio podcast

Study offers clues to making vaccine for infant respiratory illness

An atomic-level snapshot of a respiratory syncytial virus (RSV) protein bound to a human antibody represents a leap toward developing a vaccine for a common—and sometimes very serious—childhood disease. ...

Diseases, Conditions, Syndromes created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Advanced cancers destined to recur after treatment with single drugs that 'target' tumor cells: study

Targeted cancer cell therapies using man-made proteins dramatically shrink many tumors in the first few months of treatment, but new research from Johns Hopkins scientists finds why the cells all too often become resistant, ...

Cancer created Jun 13, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Major advance in the treatment of Hendra virus reported

A collaborative research team from Boston University School of Medicine (BUSM), the Uniformed Services University of the Health Sciences (USU), the University of Texas Medical Branch (UTMB) and Galveston National ...

Medical research created Oct 19, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Humabs discovers the first antibody to neutralize both group 1 and group 2 influenza A viruses

A paper published today in the scientific research journal Science, describes a novel, proprietary monoclonal antibody (FI6) discovered in a collaboration between Humabs BioMed SA, the Institute for Research in Biomedicine ("IRB" ...

Medical research created Jul 28, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Patients with chronic fatigue use additional areas of brain when using memory

(Medical Xpress)—Scientists studying the brain scans of chronic fatigue patients have found they use additional brain regions to do simple tasks requiring attention. This may explain the problems many sufferers ...

Diseases, Conditions, Syndromes created Apr 23, 2013 | popularity 5 / 5 (1) | comments 0

Study confirms everolimus can overcome trastuzumab resistance in HER-2 positive early breast cancer

A study that aimed to understand how the cancer drug everolimus helps overcome the resistance breast cancers can develop to trastuzumab has left researchers contemplating a puzzle.

Cancer created May 02, 2013 | popularity not rated yet | comments 0

Monoclonal antibodies

Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are identical because they are produced by one type of immune cell that are all clones of a single parent cell. Given almost any substance, it is possible to create monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the generic drug name ends in -mab (see "Nomenclature of monoclonal antibodies").

For more information about Monoclonal antibodies, read the full article at Wikipedia.
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