News tagged with mouse model
Related topics: stem cells , cancer cells , cells , immune cells , animal model
Gene 'switch' may explain DiGeorge syndrome severity
The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.
Genetics
Aug 23, 2012 |
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Experimental combo treatment worsens type 1 diabetes
(HealthDay)—A treatment regimen that is effective in preventing diabetes in a mouse model of the disease leads to worsening disease in patients with type 1 diabetes, according to a study published online ...
Diabetes
Aug 24, 2012 |
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New model of muscular dystrophy provides insight into disease development
Muscular dystrophy is a complicated set of genetic diseases in which genetic mutations affect the various proteins that contribute to a complex that is required for a structural bridge between muscle cells and the extracellular ...
Medical research
Aug 27, 2012 |
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'Humanized' mice enable malaria research breakthrough
A novel human liver-chimeric mouse model developed at Oregon Health & Science University and Yecuris Corporation has made possible a research breakthrough at Seattle Biomedical Research Institute that will ...
Medical research
Sep 10, 2012 |
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Like prostate cancer, bladder cancer patients may benefit from anti-androgen therapy
Bladder cancer patients whose tumors express high levels of the protein CD24 have worse prognoses than patients with lower CD24. A University of Colorado Cancer Center study published today in the Proceedings of the National Ac ...
Cancer
Sep 24, 2012 |
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Inheritance of mitochondrial disease determined when mother is still an embryo
(Medical Xpress)—The risk of a child to inherit mitochondrial diseases - i. e. malfunction in what is usually referred to as the power plants of the cell - is largely decided when the future mother herself is still an embryo. ...
Genetics
Oct 08, 2012 |
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Novel mechanisms underlying major childhood neuromuscular disease identified
A study by scientists from the Motor Neuron Center at Columbia University Medical Center (CUMC) suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results ...
Medical research
Oct 11, 2012 |
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Potential cure for Chagas disease
A Murdoch University international collaborative project has found a potential cure for the deadly Chagas disease.
Diseases, Conditions, Syndromes
Oct 25, 2012 |
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Study finds diabetes raises levels of proteins linked to Alzheimer's features
Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. ...
Alzheimer's disease & dementia
Oct 26, 2012 |
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Researchers increase understanding of genetic risk factor for type 1 diabetes
As part of their ongoing research on the role of genes in the development of type 1 diabetes, Joslin Diabetes Center scientists, in collaboration with scientists at the University of Würzburg, have demonstrated ...
Diabetes
Nov 28, 2012 |
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Enzyme inhibition protects against Huntington's disease damage in two animal models
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal ...
Neuroscience
Nov 29, 2012 |
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Researchers find new target for Alzheimer's drug development
Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.
Alzheimer's disease & dementia
Dec 03, 2012 |
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Researchers make breakthrough in arthritis research
Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.
Medical research
Dec 03, 2012 |
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Uncovering a flaw in drug testing for chronic anxiety disorder
Pre-clinical trials—the stage at which medications or therapies are tested on animals like laboratory mice—is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before ...
Medical research
Dec 13, 2012 |
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Neurons die in Alzheimer's because of faulty cell cycle control before plaques and tangles appear
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia
Dec 17, 2012 |
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