Medical research

How neuromuscular connections are maintained after nerve lesions

After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers at the University of Basel's ...

Neuroscience

Testing new drugs with 'ALS-on-a-chip'

There is no cure for amyotrophic lateral sclerosis (ALS), a disease that gradually kills off the motor neurons that control muscles and is diagnosed in nearly 6,000 people per year in the United States.

Medical research

Stem cells may be the key to staying strong in old age

University of Rochester Medical Center researchers have discovered that loss of muscle stem cells is the main driving force behind muscle decline in old age in mice. Their finding challenges the current prevailing theory ...

Neuroscience

Novel therapy delays muscle atrophy in Lou Gehrig's disease model

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig's disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels ...

Diseases, Conditions, Syndromes

Fasudil bypasses genetic cause of spinal birth defect

Scientists from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that a drug called fasudil can extend the average lifespan of mice with Spinal muscular atrophy (SMA) from ...

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