Polycythaemia vera is a chronic malignant disease of the haematopoietic system and is treated with interferon-alpha-based drugs, in most cases with long-lasting success. However, in some cases this therapy is unsuccessful ...
Sep 8, 2020
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Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are a group of rare malignancies with overlapping features from myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) that include a variety of diseases ...
Jul 1, 2020
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In an effort to improve the survival of patients with myeloproliferative neoplasms, a type of leukemia, researchers inhibited a specific protein (alpha5beta1 integrin) to decrease the number of large bone marrow cells (megakaryocytes) ...
Jun 19, 2020
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Myeloproliferative neoplasms are blood diseases that affect the normal production of blood cells in the bone marrow. According to the World Health Organization (WHO) classification, myeloproliferative neoplasms are divided ...
Apr 30, 2020
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A popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Medicine at Mount Sinai report in a study published in Scientific Reports in November.
Nov 12, 2019
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A multi-institutional clinical trial has given good results for a targeted therapy to treat a rare, aggressive blood cancer known as blastic plasmacytoid dendritic-cell neoplasm (BPDCN). Details on the trial, which supported ...
Apr 24, 2019
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New research led by Cancer Council Queensland and Curtin University has investigated the patterns and trends of a rare group of blood cancers known as myeloproliferative neoplasms (MPN) for the first time in Australia.
Mar 22, 2019
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The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments ...
Feb 8, 2019
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Chronic myelomonocytic leukemia (CMML) is a rare disease with overlapping features of two categories of bone marrow and blood cell disorders that poses challenges in clinical management. Joint recommendations on diagnosis ...
Nov 30, 2018
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The latest in a series of congressionally mandated biennial reviews of the evidence of health problems that may be linked to exposure to Agent Orange and other herbicides used during the Vietnam War found sufficient evidence ...
Nov 15, 2018
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