Scientists at the Stowers Institute for Medical Research have reported a detailed description of how function-impairing mutations in polr1c and polr1d genes cause Treacher Collins syndrome (TCS), a rare congenital craniofacial ...
Jul 22, 2016
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Caltech scientists have converted cells of the lower-body region into facial tissue that makes cartilage, in new experiments using bird embryos. The researchers discovered a "gene circuit," composed of just three genes, that ...
Jun 27, 2016
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Johns Hopkins researchers report they have inadvertently found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy (DMD).
May 26, 2016
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To grow or to specialise? To remain stationary or initiate migration? How do cells know what to do and how they should develop? The Hippo/YAP signalling pathway plays a crucial role when the cells of the neural crest – ...
Mar 22, 2016
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Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology ...
Feb 25, 2016
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Neural crest cells arise early in the development of vertebrates, migrate extensively through the embryo, and differentiate to give rise to a wide array of diverse derivatives. Their contributions include a large proportion ...
Feb 3, 2016
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Researchers at Boston Children's Hospital have, for the first time, visualized the origins of cancer from the first affected cell and watched its spread in a live animal. Their work, published in the January 29th issue of ...
Jan 28, 2016
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Neuroblastoma is the third most common type of tumour in children. Its aggressive nature and the frequency of metastatic disease at diagnosis contribute to the fact that neuroblastoma accounts for almost 15 per cent of childhood ...
Jan 25, 2016
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Whitehead Institute researchers have created a new mouse-human modeling platform that could be used to study neural crest development as well as the modeling of a variety of diseases, including such cancers as melanoma and ...
Jan 25, 2016
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Researchers at the Virginia Bioinformatics Institute have uncovered a link between the genomes of cells originating in the neural crest and development of tumors—a discovery that could lead to new ways to diagnose and treat ...
Aug 5, 2015
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