Like people, neurons need to talk to one another. But instead of turning thoughts into words, these cells convert electrical signals into chemical ones. For nearly 30 years, biochemist Edwin Chapman has studied how one protein ...
May 1, 2020
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In the human genome, small sections of DNA have been found to be duplicated (copied) or deleted in a small number of people, a phenomenon known as Copy Number Variation. Some of these genetic changes are linked to an increased ...
Apr 21, 2020
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An international team of researchers that pooled genetic samples from developmentally disabled patients from around the world has identified dozens of new mutations in a single gene that appears to be critical for brain development.
Mar 4, 2020
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Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes. In a new study, researchers evaluated the effects of over 300 pairwise ...
Feb 14, 2020
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Many neurodevelopmental disorders such as epilepsy, schizophrenia, and autism have been linked to disruption of the key neurotransmitter GABA, but the underlying causes of the disruptions have been difficult to pinpoint. ...
Oct 17, 2019
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Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a ...
Jul 30, 2019
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Autism and other neurodevelopmental disorders often aren't diagnosed until a child is a few years of age, when behavioral interventions and speech/occupational therapy become less effective. But new research this week in ...
Jul 24, 2019
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Researchers have discovered a mysterious group of neurons in the amygdala—a key center for emotional processing in the brain—that stay in an immature, prenatal developmental state throughout childhood. Most of these cells ...
Jun 24, 2019
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Using the genome-editing system CRISPR, researchers at MIT and in China have engineered macaque monkeys to express a gene mutation linked to autism and other neurodevelopmental disorders in humans. These monkeys show some ...
Jun 12, 2019
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A new study challenges the presumption that people born with developmental brain disorders such as severe autism will benefit from medical interventions only if treated during a narrow window in infancy or early childhood.
Apr 26, 2019
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