Medical research

Keep calm! How blood vessels are kept in check

The inner surface of blood vessels is lined by a wafer-thin layer of cells known as the endothelium, which forms a crucial barrier between blood and the surrounding tissue. The single-layered cell structure promotes the exchange ...

Medical research

A novel marker of adult human neural stem cells discovered

The mammalian center for learning and memory, hippocampus, has a remarkable capacity to generate new neurons throughout life. Newborn neurons are produced by neural stem cells (NSCs) and they are crucial for forming neural ...

Neuroscience

Alzheimer research: Noise-inducing neurons shut down memories

Neurons that are responsible for new experiences interfere with the signals of neurons that contain memories and thereby disturb the recall of memories—at least in mice. The research group of Martin Fuhrmann of the German ...

Oncology & Cancer

Turning on the 'off switch' in cancer cells

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway ...

Medical research

S1P and its receptor: New approaches to cancer?

In 1998, when Timothy Hla, Ph.D., and his colleagues identified and cloned the receptor for sphingosine-1-phosphate (S1P), it generated a lot of excitement. S1P, a lipid originally discovered in the 1960s, was known to play ...

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