Genetics

Biodistribution of AAV gene transfer vectors in nonhuman primate

The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration. ...

Neuroscience

Crowd-sourcing optogenetics data to tackle neurological diseases

Around the world, some 50 million people have epilepsy, with more than 3 million in the United States alone. It's one of the most common neurological diseases globally, characterized by recurrent seizures in part or all of ...

Neuroscience

New neuron type discovered only in primate brains

Neuropsychiatric illnesses like schizophrenia and autism are a complex interplay of brain chemicals, environment, and genetics that requires careful study to understand the root causes. Scientists have traditionally relied ...

Diseases, Conditions, Syndromes

Nasal vaccine against COVID-19 prevents infection in mice

Scientists at Washington University School of Medicine in St. Louis have developed a vaccine that targets the SARS-CoV-2 virus, can be given in one dose via the nose and is effective in preventing infection in mice susceptible ...

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