News tagged with notch signaling
Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance
A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...
Cancer
Apr 01, 2013 |
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Differences in bone healing in mice may hold answers to bone healing for seniors
(Medical Xpress)—By studying the underlying differences in gene expression during healing after a bone break in young versus aged mice, Jaimo Ahn, MD, PhD, assistant professor of Orthopaedic Surgery at the Perelman School ...
Surgery
Mar 21, 2013 |
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A better bone marrow transplant: Preventing graft-versus-host disease
Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Medical research
Mar 01, 2013 |
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Ruling the airways: Notch controls bronchial cell fates and distributions
Nestled deep within the body, the epithelial lining of the respiratory system is nonetheless seriously exposed. Its direct contact with environmental air necessitates protective mechanisms that both seal ...
Medical research
Jan 22, 2013 |
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At the right place at the right time—new insights into muscle stem cells
Muscles have a pool of stem cells which provides a source for muscle growth and for regeneration of injured muscles. The stem cells must reside in special niches of the muscle for efficient growth and repair.
Medical research
Sep 17, 2012 |
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Scientists find new mechanism by which cell signaling pathway contributes to rheumatoid arthritis development
A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence ...
Immunology
May 20, 2012 |
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Gatekeeper signal controls skin inflammation
A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" that, ...
Medical research
Jan 26, 2012 |
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Previously unconnected molecular networks conspire to promote cancer
An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson ...
Cancer
Dec 22, 2011 |
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Study reveals origins of a cancer affecting the blood and bone marrow
A new study by the NYU Cancer Institute, an NCI-designated cancer center, sheds light on the origins of myeloid leukemia, a type of blood cancer that affects children and adults. The researchers discovered that novel mutations ...
Cancer
May 12, 2011 |
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Buenos 'notch-es': Universal signaling pathway found to regulate sleep
Sleeping worms have much to teach people, a notion famously applied by the children's show "Sesame Street," in which Oscar the Grouch often reads bedtime stories to his pet worm Slimy. Based on research with their own worms, ...
Medical research
May 05, 2011 |
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