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Massive study closes in on cancers risk markers

Cancer research has taken a huge leap forward with scientists now able to identify more than 80 genetic markers found to increase the risk of breast, ovarian and prostate cancer. The COGS international research ...

Genetics created May 15, 2013 | popularity 5 / 5 (2) | comments 0

New study discovers genomic variant that increases risk of some brain tumors

People who carry a "G" instead of an "A" at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the ...

Genetics created Aug 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Gene mutation as cause of breast and ovarian cancer

A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Single change in genetic sequence can significantly impact BMI variability

(Medical Xpress)—One small change to the DNA sequence can cause more weighty changes to the human body, according to a new study released today.

Genetics created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

New method helps link genomic variation to protein production

Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according ...

Genetics created Nov 06, 2012 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

ECE: Gene variants linked to reduced male fertility

(HealthDay)—Particular gene variants of follicle stimulating hormone (FSH) and its receptor are associated with significantly reduced fertility in men, according to a study presented at the annual European ...

Genetics created May 03, 2013 | popularity 5 / 5 (1) | comments 0

First evidence for genetic cause for Barrett's oesophagus found

Genetic variations that are linked with the onset of Barrett's oesophagus (BE), a pre-cancerous condition of the lower end of the gullet, have been identified for the first time. The discovery of variations in regions on ...

Genetics created Sep 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Three new genetic links to breast cancer identified

(Medical Xpress) -- An international team of researchers has identified three new genetic loci associated with an increased susceptibility to breast cancer. As described in their paper published in Nature Ge ...

Genetics created Jan 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

Genome-wide study identifies eight new susceptibility loci for atopic dermatitis

Japanese researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population. The findings, ...

Genetics created Oct 07, 2012 | popularity 1 / 5 (1) | comments 0 | with audio podcast

Study: Gene-gene interactions important to trait variance

(Medical Xpress)—Gaining more insight into predicting how genes affect physical or behavioral traits by charting the genotype-phenotype map holds promise to speed discoveries in personalized medicine. But ...

Genetics created Sep 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Chemists determine one way tumors meet their growing need

Behaving something like ravenous monsters, tumors need plentiful supplies of cellular building blocks such as amino acids and nucleotides in order to keep growing at a rapid pace and survive under harsh conditions. ...

Cancer created Aug 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Discovery could reduce chemotherapy's side effects

A team of researchers at Duke University has determined the structure of a key molecule that can carry chemotherapy and anti-viral drugs into cells, which could help to create more effective drugs with fewer effects to healthy ...

Cancer created Mar 11, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists discover gene switch important in cancer

Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published ...

Cancer created Nov 01, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study examines effects of genetic variants for infants with neonatal abstinence syndrome

Among infants with neonatal abstinence syndrome (NAS; caused by in utero opioid exposure), variants in certain genes were associated with a shorter length of hospital stay and less need for treatment, preliminary findings ...

Diseases, Conditions, Syndromes created Apr 30, 2013 | popularity not rated yet | comments 0

Researchers create powerful new method to analyze genetic data

University of Texas Medical Branch at Galveston researchers have developed a powerful visual analytical approach to explore genetic data, enabling scientists to identify novel patterns of information that could be crucial ...

Genetics created Jun 12, 2012 | popularity not rated yet | comments 1 | with audio podcast

Nucleotide

Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. Additionally, nucleotides play central roles in metabolism. In that capacity, they serve as sources of chemical energy (adenosine triphosphate and guanosine triphosphate), participate in cellular signaling (cyclic guanosine monophosphate and cyclic adenosine monophosphate), and are incorporated into important cofactors of enzymatic reactions (coenzyme A, flavin adenine dinucleotide, flavin mononucleotide, and nicotinamide adenine dinucleotide phosphate).

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