"Despite the prevalence and societal costs of pain in the United States, investment in pain medication development is low, due in part to poor understanding of the probability of successful development of such medications," ...
Jun 21, 2022
1
138
Opioids are not among the most effective—or longest lasting—options available for relief from acute dental pain, a new examination of the results from more than 460 published studies has found.
Apr 17, 2018
7
4801
None of us has the brain we were born with. Brains grow and adapt. This process, called neuroplasticity, doesn't end when you step out of the classroom. Even habits—reaching for cookies when stressed out, keeping your head ...
Aug 1, 2018
0
1558
The story line sounds familiar: a popular pain drug becomes a new way to get high as prescribing by doctors soars.
May 4, 2018
2
2087
Since its approval in 1995, the opioid tramadol (marketed as ConZip and Ultram) has become a widely prescribed remedy for osteoarthritis and other painful indications, in part because it presents a lesser risk for some side ...
Aug 28, 2019
2
886
China has some of the strictest regulation of opioids in the world, but OxyContin and other pain pills are sold illegally online by vendors that take advantage of China's major e-commerce and social media sites, including ...
Dec 31, 2019
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3
Canada has seen a drastic shift in the unregulated drug supply with the emergence of benzodiazepine-adulterated opioids (also known as "benzo-dope"). Benzodiazepines have been detected in as many as 60 percent of overdose ...
Aug 12, 2021
0
574
The U.S. methamphetamine mortality rate increased fiftyfold between 1999 and 2021, with most of the added deaths also involving heroin or fentanyl, researchers report in the American Journal of Public Health.
Feb 20, 2023
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73
A new study led by UC San Francisco scientists shows that brain cells, or neurons, react differently to opioid substances created inside the body - the endorphins responsible for the "natural high" that can be produced by ...
May 10, 2018
1
429
While the opioid overdose and death epidemic continues to worsen across the United States, medications such as methadone, buprenorphine and extended-release naltrexone are proven to reduce opioid overdoses by more than 50 ...
Aug 4, 2022
0
46
